Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   EXA24_RS05645 Genome accession   NZ_CP036376
Coordinates   1089519..1090832 (-) Length   437 a.a.
NCBI ID   WP_000042576.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain Sag153     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1084519..1095832
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA24_RS05625 (EXA24_05775) - 1085999..1086772 (-) 774 WP_000622398.1 DUF3307 domain-containing protein -
  EXA24_RS05630 (EXA24_05780) - 1086762..1087448 (-) 687 WP_000280308.1 SatD family protein -
  EXA24_RS05635 (EXA24_05785) ffh 1087515..1089080 (-) 1566 WP_000863589.1 signal recognition particle protein -
  EXA24_RS05640 (EXA24_05790) - 1089098..1089430 (-) 333 WP_000402075.1 putative DNA-binding protein -
  EXA24_RS05645 (EXA24_05795) ciaH 1089519..1090832 (-) 1314 WP_000042576.1 HAMP domain-containing sensor histidine kinase Regulator
  EXA24_RS05650 (EXA24_05800) ciaR 1090816..1091496 (-) 681 WP_000590620.1 response regulator transcription factor Regulator
  EXA24_RS05655 (EXA24_05805) - 1091658..1094207 (-) 2550 WP_079219439.1 M1 family metallopeptidase -
  EXA24_RS05660 (EXA24_05810) phoU 1094353..1095006 (-) 654 WP_000946330.1 phosphate signaling complex protein PhoU -
  EXA24_RS05665 (EXA24_05815) pstB 1095040..1095798 (-) 759 WP_000193363.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 49678.12 Da        Isoelectric Point: 9.4961

>NTDB_id=348295 EXA24_RS05645 WP_000042576.1 1089519..1090832(-) (ciaH) [Streptococcus agalactiae strain Sag153]
MSKPIKISKFKKNVSDSHFIHFFTVFSGIFLVMTVIILQVMRYGVYSSVDSSLKYISTHPKNYINMVMSRTAAYLDNSNI
ASVKLKPGGQTVANTDIILFTSEEEVINYFDAFSNYQFLKPNKKNLGGISELTLTNIFGQDETYHAVTVKVNNPAYPNVT
YMTAIVNIDQLVNAKERYEKIIIFVMTTFWIISIGASIYLAKWAQKPIIENYERQKAFVENASHELRTPLAVLQNRLETL
FRKPNATILENSENIASSLDEVRNMRILTTNLLNLARRDDGIKPELAVIKPTLFDSIFENYDLIAQENGKNFTGHNMIQD
SFKTDKTLLKQLMTILFDNAIKYTDNDGSIDFTISETDKYLFLEIADNGPGISEEDKVRIFDRFYRVDKARTRQQGGFGL
GLSLAQQIVNSLRGNITVIDNKPRGSIFKIKLPKVKG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=348295 EXA24_RS05645 WP_000042576.1 1089519..1090832(-) (ciaH) [Streptococcus agalactiae strain Sag153]
ATGTCGAAACCGATTAAGATAAGTAAATTCAAAAAAAATGTCTCAGATAGTCATTTTATCCATTTTTTCACAGTTTTTAG
TGGTATTTTTCTGGTTATGACTGTTATCATCCTCCAAGTCATGCGCTATGGTGTTTATTCTTCTGTTGATAGTAGTTTAA
AGTATATCAGTACCCATCCTAAAAATTACATCAATATGGTTATGTCACGTACTGCTGCCTACCTAGATAACTCCAATATC
GCAAGTGTCAAGTTAAAACCCGGCGGTCAGACAGTAGCTAATACTGATATTATTCTTTTTACATCAGAAGAAGAAGTCAT
TAACTATTTTGACGCATTTTCAAACTATCAGTTTTTAAAACCTAATAAAAAAAATCTAGGTGGCATTAGTGAATTAACTT
TAACCAACATCTTTGGTCAAGATGAGACATATCATGCTGTCACCGTAAAAGTTAATAACCCTGCTTATCCTAATGTGACT
TACATGACAGCTATTGTTAATATTGATCAATTAGTAAATGCTAAAGAACGCTATGAAAAAATTATTATATTTGTCATGAC
TACTTTTTGGATTATTTCAATTGGAGCAAGTATCTACTTAGCTAAATGGGCACAAAAACCGATTATAGAAAACTACGAAA
GACAGAAGGCTTTTGTCGAAAATGCTAGCCACGAGCTGCGTACTCCCCTAGCTGTCTTACAAAATCGCCTAGAAACGCTA
TTCAGAAAACCGAATGCCACCATTTTAGAAAATAGTGAAAATATCGCTTCAAGTCTAGATGAAGTACGAAATATGCGTAT
TTTAACCACTAATCTTTTAAACTTAGCAAGACGTGATGATGGAATCAAACCAGAATTAGCTGTTATTAAGCCTACACTTT
TTGATAGTATCTTTGAGAATTATGATCTAATCGCCCAAGAGAATGGTAAAAATTTTACTGGACATAATATGATCCAAGAT
AGTTTCAAAACAGATAAGACACTGCTAAAACAACTCATGACTATTTTATTTGATAATGCTATAAAATATACTGACAATGA
TGGTAGCATTGACTTTACCATATCTGAAACTGATAAGTATCTCTTTTTAGAAATCGCTGATAATGGACCAGGAATTTCAG
AGGAGGATAAAGTCAGAATTTTTGATCGTTTTTACCGTGTTGACAAAGCAAGAACACGACAACAAGGAGGGTTTGGCCTC
GGCCTTTCTTTAGCTCAACAAATCGTTAACTCACTGCGAGGTAATATTACAGTAATTGATAATAAACCTAGAGGCAGTAT
TTTTAAGATAAAACTACCAAAAGTAAAAGGTTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(216-281)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

60.373

98.169

0.593
  ciaH Streptococcus pneumoniae Rx1

52.143

96.11

0.501
  ciaH Streptococcus pneumoniae D39

52.143

96.11

0.501
  ciaH Streptococcus pneumoniae R6

52.143

96.11

0.501
  ciaH Streptococcus pneumoniae TIGR4

52.143

96.11

0.501

Multiple sequence alignment