Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   SSUBM407_RS00325 Genome accession   NC_012926
Coordinates   55418..56323 (+) Length   301 a.a.
NCBI ID   WP_012775468.1    Uniprot ID   A0A0H3MSK4
Organism   Streptococcus suis BM407     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 50418..61323
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSUBM407_RS00305 (SSUBM407_0042) - 50505..52217 (+) 1713 WP_012774887.1 ABC transporter ATP-binding protein -
  SSUBM407_RS10615 - 52319..52492 (+) 174 WP_011921669.1 hypothetical protein -
  SSUBM407_RS00310 (SSUBM407_0043) ruvB 52787..53788 (+) 1002 WP_004195448.1 Holliday junction branch migration DNA helicase RuvB -
  SSUBM407_RS00315 (SSUBM407_0044) - 53788..54534 (+) 747 WP_011921670.1 GNAT family N-acetyltransferase -
  SSUBM407_RS00320 (SSUBM407_0045) - 54536..55171 (+) 636 WP_011921671.1 HAD-IA family hydrolase -
  SSUBM407_RS00325 (SSUBM407_0046) comR 55418..56323 (+) 906 WP_012775468.1 helix-turn-helix domain-containing protein Regulator
  SSUBM407_RS00330 (SSUBM407_0047) - 56728..57891 (+) 1164 WP_011921673.1 IS110 family transposase -
  SSUBM407_RS00335 (SSUBM407_0049) - 58429..59367 (-) 939 WP_011921674.1 IS4 family transposase -
  SSUBM407_RS00340 (SSUBM407_0050) - 59507..60727 (+) 1221 WP_012774890.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -

Sequence

Protein


Download         Length: 301 a.a.        Molecular weight: 35575.51 Da        Isoelectric Point: 4.6492

>NTDB_id=34641 SSUBM407_RS00325 WP_012775468.1 55418..56323(+) (comR) [Streptococcus suis BM407]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLGLYELMPDYVSLPERYSK
LKFDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYEL
NDLLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQ
STQDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide


Download         Length: 906 bp        

>NTDB_id=34641 SSUBM407_RS00325 WP_012775468.1 55418..56323(+) (comR) [Streptococcus suis BM407]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAG
CTGAAGTTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAAT
CTATGACGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAG
AGTCAGGTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTG
AATGATTTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTT
GAAAATTATAGAGCATTTACATGAGCAAATCAATATCATCAACTCAAATGATTTATTTGTTTTACGAGACACGCTATTAT
CTTGTGTAAATATATTAGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGACAGTGTAGATAAGATTATACAG
TCGACACAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGA
TGAGGCAGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAGAAGATTGAAG
AAGATTGGAGAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(75-296)

Helix-turn-helix domain (HTH_31)

(5-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MSK4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

99.336

100

0.993
  comR Streptococcus suis 05ZYH33

99.336

100

0.993
  comR Streptococcus suis D9

61.716

100

0.621
  comR Streptococcus mutans UA159

44

99.668

0.439
  comR Streptococcus pyogenes MGAS315

37.584

99.003

0.372

Multiple sequence alignment