Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   GD578_RS15450 Genome accession   NZ_CP045560
Coordinates   3209197..3209871 (-) Length   224 a.a.
NCBI ID   WP_153518674.1    Uniprot ID   -
Organism   Acinetobacter nosocomialis strain AC1530     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3204197..3214871
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GD578_RS15430 (GD578_15635) - 3204504..3205388 (+) 885 WP_002051515.1 LysR family transcriptional regulator -
  GD578_RS15435 (GD578_15645) - 3205695..3206882 (+) 1188 WP_153518672.1 ammonium transporter -
  GD578_RS15440 (GD578_15650) - 3207142..3207840 (+) 699 WP_004885453.1 phosphatase PAP2 family protein -
  GD578_RS15445 (GD578_15655) - 3207837..3209171 (-) 1335 WP_025467925.1 two-component system sensor histidine kinase PmrB -
  GD578_RS15450 (GD578_15660) ciaR 3209197..3209871 (-) 675 WP_153518674.1 response regulator transcription factor Regulator
  GD578_RS15455 (GD578_15665) - 3209886..3211535 (-) 1650 WP_031951196.1 phosphoethanolamine transferase -
  GD578_RS15460 (GD578_15670) - 3211719..3213029 (-) 1311 WP_002051240.1 DcaP family trimeric outer membrane transporter -
  GD578_RS15465 (GD578_15675) - 3213572..3214819 (-) 1248 WP_002051301.1 MFS transporter -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25516.34 Da        Isoelectric Point: 5.3091

>NTDB_id=345095 GD578_RS15450 WP_153518674.1 3209197..3209871(-) (ciaR) [Acinetobacter nosocomialis strain AC1530]
MTKILMIEDDFMIAESTTTLLQYHQFEVEWVNNGLDGLAQLAKNKFDLILLDLGLPMMDGMQVLKQIRQRAATPVLIISA
RDQLQNRVDGLNLGADDYLIKPYEFDELLARIHALLRRSGVEAQLASQDQLLESGDLVLNVEQHIATFKGQRIDLSNREW
AILIPLMSHPNKIFSKANLEDKLYDFDSDVTSNTIEVYVHHLRAKLGKDFIRTIRGLGYHLGQS

Nucleotide


Download         Length: 675 bp        

>NTDB_id=345095 GD578_RS15450 WP_153518674.1 3209197..3209871(-) (ciaR) [Acinetobacter nosocomialis strain AC1530]
ATGACAAAAATCTTGATGATTGAAGATGATTTTATGATTGCAGAATCAACAACGACGTTGCTGCAATATCATCAATTTGA
GGTGGAATGGGTCAATAACGGTTTAGATGGTTTGGCCCAATTAGCAAAGAATAAGTTTGATCTCATTCTTTTAGACTTGG
GATTGCCAATGATGGATGGTATGCAAGTTTTAAAGCAGATTCGTCAAAGAGCAGCAACACCAGTCTTGATTATCTCTGCA
CGTGACCAACTGCAAAACCGTGTTGATGGTCTGAATTTGGGAGCAGATGATTACTTAATTAAGCCTTATGAGTTTGATGA
ATTACTCGCTCGTATTCATGCTTTATTACGCCGTAGTGGCGTAGAGGCTCAACTTGCAAGCCAAGATCAACTACTAGAAA
GCGGTGATCTGGTTTTAAATGTTGAACAGCACATTGCAACGTTTAAAGGGCAACGTATTGATTTATCGAATCGTGAATGG
GCAATCTTGATTCCGCTTATGAGTCATCCAAATAAAATTTTCTCAAAAGCTAATTTGGAAGATAAGTTATATGACTTTGA
TAGTGATGTGACCAGCAACACGATTGAGGTATATGTCCATCATTTAAGGGCTAAGTTGGGTAAAGACTTTATTCGAACTA
TCCGAGGACTGGGTTACCATTTAGGGCAATCATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.496

100

0.388
  ciaR Streptococcus pneumoniae D39

38.496

100

0.388
  ciaR Streptococcus pneumoniae R6

38.496

100

0.388
  ciaR Streptococcus pneumoniae TIGR4

38.496

100

0.388
  ciaR Streptococcus mutans UA159

37.445

100

0.379
  micA Streptococcus pneumoniae Cp1015

36.087

100

0.371

Multiple sequence alignment