Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   SALIVB_RS05550 Genome accession   NC_015760
Coordinates   1246595..1247935 (-) Length   446 a.a.
NCBI ID   WP_013990681.1    Uniprot ID   -
Organism   Streptococcus salivarius CCHSS3     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1241595..1252935
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SALIVB_RS05525 (SALIVB_1140) yidA 1242042..1242848 (+) 807 WP_004182607.1 sugar-phosphatase -
  SALIVB_RS05530 (SALIVB_1141) - 1242848..1244062 (+) 1215 WP_004182608.1 aminoacyltransferase -
  SALIVB_RS05535 (SALIVB_1142) tnpA 1244201..1244674 (-) 474 WP_013990678.1 IS200/IS605 family transposase -
  SALIVB_RS10555 - 1244911..1245187 (-) 277 Protein_1051 ISL3 family transposase -
  SALIVB_RS05540 (SALIVB_1144) - 1245359..1245718 (-) 360 WP_013990679.1 YbaN family protein -
  SALIVB_RS05545 (SALIVB_1145) vicX 1245777..1246589 (-) 813 WP_013990680.1 MBL fold metallo-hydrolase Regulator
  SALIVB_RS05550 (SALIVB_1146) vicK 1246595..1247935 (-) 1341 WP_013990681.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SALIVB_RS05555 (SALIVB_1147) yycF 1247928..1248635 (-) 708 WP_002884978.1 response regulator YycF -
  SALIVB_RS05560 (SALIVB_1148) - 1248920..1249687 (+) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  SALIVB_RS05565 (SALIVB_1149) - 1249697..1250530 (+) 834 WP_013990682.1 transporter substrate-binding domain-containing protein -
  SALIVB_RS05570 (SALIVB_1150) - 1250548..1251246 (+) 699 WP_002886251.1 amino acid ABC transporter permease -
  SALIVB_RS05575 (SALIVB_1151) - 1251258..1251908 (+) 651 WP_002886253.1 amino acid ABC transporter permease -
  SALIVB_RS05580 (SALIVB_1152) endA 1251987..1252868 (-) 882 WP_013990683.1 DNA/RNA non-specific endonuclease Machinery gene

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50929.21 Da        Isoelectric Point: 5.1606

>NTDB_id=34210 SALIVB_RS05550 WP_013990681.1 1246595..1247935(-) (vicK) [Streptococcus salivarius CCHSS3]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDFETATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=34210 SALIVB_RS05550 WP_013990681.1 1246595..1247935(-) (vicK) [Streptococcus salivarius CCHSS3]
ATGACTAGTATTGGCTTAAATATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTGGCTTTCTACTTTAT
TTTTCTTGCATATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGGGTCAAGTCCTTAATGGCAGGTA
ACTATAACGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGATGTC
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTTTCTTACATGAGTGATGGGGTTAT
TGCGACAAATCGTCGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTTTGAAACAGCGA
CACAGATGTCCATTTTAGATTTATTAGATGGTGAAAATCCCTATACTTATAGTGAATTGCTGTCTAAGACTCCTGAAATT
CATTTGTCACGTCGAGATGCTAACGATGAGTTTGTGACCCTACGCGTTAACTTTGCCCTAATTCGTAAAGAATCAGGTTT
TATCTCAGGTTTGGTTGCCGTTCTTCATGATGCTACTGAGCAGGAAAAAGAAGAGCGGGAACGTCGACTTTTCGTCTCAA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCCTATCTGGAGGCACTTGATGATGGAGCTCTCGATGAA
GAGATTGCACCTAACTTCATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCATT
GTCACGTATTGACAATAAGAGTACCCAACTTGACGTTGAGATGACCAATTTCACGGCCTTCATGACCTATATCTTGAATC
GTTTTGATCAGATTAAAAGTCAAGAAACCAATACAGGTAAAACTTACGAAATCATTCGCGATTATCCGGTAAACTCAATT
TGGGTGGAGATTGATACAGATAAGATGACCCAGGTCGTGGATAATATTCTTAATAATGCCATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGACTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAAGATTTGCCTTTGATTTTCGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCCCAAGGTGGAACTGGTCTA
GGCTTGTCCATTGCAAAAGAAATCATTAAACAACATAAGGGCTTTATTTGGGCTAAAAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterProScan.

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92.825

0.684
  micB Streptococcus pneumoniae Cp1015

67.667

97.085

0.657

Multiple sequence alignment