Detailed information NTG0340476

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: FOB76_RS04015
• Genome accession: NZ_CP044093
• Coordinates: 752810..753808 (-)
• Length: 332 a.a.
• NCBI ID: WP_002987726.1
• Uniprot ID: Q1JP25
• Organism: Streptococcus pyogenes strain FDAARGOS_668
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 747810..758808

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOB76_RS04000 (FOB76_04000)	-	750038..751813 (-)	1776	WP_002987732.1	acyltransferase family protein	-
FOB76_RS04005 (FOB76_04005)	-	751810..752211 (-)	402	WP_002987730.1	MORN repeat-containing protein	-
FOB76_RS04010 (FOB76_04010)	-	752235..752672 (-)	438	WP_002987727.1	low molecular weight protein-tyrosine-phosphatase	-
FOB76_RS04015 (FOB76_04015)	ruvB	752810..753808 (-)	999	WP_002987726.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
FOB76_RS09760	comS	753855..753950 (-)	96	WP_198462994.1	quorum-sensing system DWW-type pheromone	Regulator
FOB76_RS04020 (FOB76_04020)	comR	754034..754945 (-)	912	WP_002986681.1	transcriptional regulator Rgg4/ComR	Regulator
FOB76_RS04025 (FOB76_04025)	purB	755078..756370 (-)	1293	WP_002987723.1	adenylosuccinate lyase	-
FOB76_RS04030 (FOB76_04030)	-	756739..758079 (-)	1341	WP_002987721.1	hypothetical protein	-

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 37585.14 Da
• Isoelectric Point: 5.1689

>NTDB_id=340476 FOB76_RS04015 WP_002987726.1 752810..753808(-) (ruvB) [Streptococcus pyogenes strain FDAARGOS_668]
MARILDNDVMGNEEFSDRTLRPQYLREYIGQDKVKEQFAIFIEAAKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPAVEKAGDLVAILNELEPGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPRIANRLLKRVRDYAQIIGDGIIT
AQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGGPVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQK
AYRHLGYPYQNT

Nucleotide

• Length: 999 bp

>NTDB_id=340476 FOB76_RS04015 WP_002987726.1 752810..753808(-) (ruvB) [Streptococcus pyogenes strain FDAARGOS_668]
ATGGCTAGAATTTTAGACAATGATGTAATGGGAAATGAGGAGTTTTCGGATCGGACTCTTCGCCCTCAATATCTACGCGA
ATATATTGGACAAGATAAAGTTAAGGAACAATTCGCTATTTTTATAGAAGCAGCTAAAAGACGTGACGAATCTTTAGACC
ATGTTTTATTATTTGGACCTCCAGGACTGGGAAAAACAACAATGGCATTTGTGATTGCCAATGAATTGGGAGTTAATTTA
AAGCAAACTTCAGGTCCTGCCGTTGAGAAAGCTGGAGATTTGGTAGCTATTTTAAATGAATTAGAACCAGGGGATATTTT
GTTTATTGATGAAATTCACCGCATGCCAATGTCTGTTGAGGAAGTACTATATAGTGCTATGGAAGACTTCTATATTGATA
TTATGATTGGCGCTGGAGATACTAGTCGTAGTATTCATTTGGATCTGCCTCCATTTACATTGATTGGTGCTACTACACGT
GCAGGCATGTTATCTAATCCCCTCAGAGCTCGTTTTGGTATCACTGGTCACATGGAATACTATCAAGAAAAGGATTTGAC
AGAGATTGTGGAGCGTACAGCTACTATTTTTGAAATAAAAATAGACCATGAAGCTGCACGGAAATTAGCTTGTCGCAGTA
GAGGAACGCCCCGCATTGCTAATCGATTACTAAAACGAGTGCGTGACTATGCTCAAATTATTGGTGATGGCATCATAACG
GCTCAAATAACTGATAGAGCTTTGACTATGTTAGATGTTGACCGCGAAGGTCTCGATTACATTGATCAGAAAATTTTACG
AACGATGATTGAGATGTATCAGGGAGGACCAGTTGGTTTGGGGACATTATCTGTGAATATTGCCGAGGAGCGTAATACAG
TTGAAGAGATGTATGAACCCTACTTAATTCAAAAAGGCTTTCTCATGCGAACACGAACAGGTCGTGTAGCGACTCAAAAG
GCTTATCGTCATCTTGGCTATCCCTATCAAAACACTTAA

Domains

Predicted by InterProScan.

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

3D structure

• AlphaFold DB: Q1JP25

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	85.152	99.398	0.846
ruvB	Streptococcus pneumoniae D39	85.152	99.398	0.846
ruvB	Streptococcus pneumoniae TIGR4	84.848	99.398	0.843
ruvB	Bacillus subtilis subsp. subtilis str. 168	58.824	97.289	0.572
ruvB	Helicobacter pylori 26695	48.936	99.096	0.485
ruvB	Synechocystis sp. PCC 6803	50.16	94.277	0.473