Detailed information NTG0339553

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: ES963_RS13355
• Genome accession: NZ_CP035390
• Coordinates: 2473340..2473957 (-)
• Length: 205 a.a.
• NCBI ID: WP_046160608.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain SRCM103641
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2468340..2478957

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES963_RS13325 (ES963_13325)	rpsT	2468641..2468907 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
ES963_RS13330 (ES963_13330)	holA	2468922..2469965 (-)	1044	WP_029317888.1	DNA polymerase III subunit delta	-
ES963_RS13335 (ES963_13335)	-	2470005..2470118 (-)	114	WP_122060479.1	hypothetical protein	-
ES963_RS13340 (ES963_13340)	yqzM	2470195..2470329 (+)	135	WP_003229983.1	YqzM family protein	-
ES963_RS13345 (ES963_13345)	comEC	2470370..2472700 (-)	2331	WP_046160607.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ES963_RS13350 (ES963_13350)	comEB	2472704..2473273 (-)	570	WP_003229978.1	ComE operon protein 2	-
ES963_RS13355 (ES963_13355)	comEA	2473340..2473957 (-)	618	WP_046160608.1	competence protein ComEA	Machinery gene
ES963_RS13360 (ES963_13360)	comER	2474041..2474862 (+)	822	WP_032726195.1	late competence protein ComER	-
ES963_RS13365 (ES963_13365)	yqeM	2474928..2475671 (-)	744	WP_046160609.1	class I SAM-dependent methyltransferase	-
ES963_RS13370 (ES963_13370)	rsfS	2475668..2476024 (-)	357	WP_014480315.1	ribosome silencing factor	-
ES963_RS13375 (ES963_13375)	yqeK	2476042..2476602 (-)	561	WP_014480316.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
ES963_RS13380 (ES963_13380)	nadD	2476592..2477161 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
ES963_RS13385 (ES963_13385)	yhbY	2477173..2477463 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-
ES963_RS13390 (ES963_13390)	aroE	2477457..2478299 (-)	843	WP_014480317.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 205 a.a.
• Molecular weight: 21738.48 Da
• Isoelectric Point: 4.7284

>NTDB_id=339553 ES963_RS13355 WP_046160608.1 2473340..2473957(-) (comEA) [Bacillus subtilis strain SRCM103641]
MNWLNQHKKAIVLAASAAVFTAIMIFLATGKNKEPVKQAVPTEAENTVVKQEANNDESSETIVIDIKGAVQHPGVYEMRT
GDRVSQAIEKAGGTSEQADEAQVNLAEILQDGTVVYIPKKGEETAVQQGGGGSVQSDGGKGALVNINTATLEELQGISGV
GPSKAEAIIAYREENGRFQTIEEITKVSGIGEKLFEKIKSSITVK

Nucleotide

• Length: 618 bp

>NTDB_id=339553 ES963_RS13355 WP_046160608.1 2473340..2473957(-) (comEA) [Bacillus subtilis strain SRCM103641]
ATGAATTGGTTGAATCAGCATAAGAAAGCAATTGTTTTAGCGGCTTCTGCGGCTGTTTTCACAGCGATTATGATCTTTCT
GGCCACAGGGAAAAATAAAGAGCCGGTGAAGCAAGCTGTACCAACAGAGGCAGAAAATACAGTGGTAAAGCAGGAAGCAA
ACAACGACGAGTCAAGCGAAACAATTGTGATAGACATCAAAGGTGCTGTTCAGCATCCTGGAGTTTATGAAATGCGAACA
GGGGACAGAGTATCTCAGGCAATTGAGAAAGCGGGCGGGACCAGTGAACAAGCAGACGAAGCGCAAGTAAATTTGGCGGA
GATTTTGCAGGACGGGACAGTGGTGTACATCCCGAAAAAGGGAGAGGAAACAGCAGTGCAGCAAGGTGGCGGAGGGTCTG
TCCAAAGCGATGGAGGGAAGGGAGCGCTGGTGAATATCAATACAGCAACCTTAGAGGAGTTACAAGGCATCTCAGGGGTG
GGGCCATCCAAAGCTGAAGCTATTATTGCATACCGGGAAGAAAACGGGCGTTTCCAAACAATTGAAGAAATCACTAAGGT
TTCAGGAATAGGTGAAAAGTTATTTGAGAAAATAAAGTCTTCCATTACAGTAAAGTGA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (63-118)

• Helix-hairpin-helix motif (HHH_3) (142-203)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Bacillus subtilis subsp. subtilis str. 168	97.561	100	0.976
comEA	Staphylococcus aureus MW2	35.909	100	0.385
comEA	Staphylococcus aureus N315	35	100	0.376