Detailed information NTG0339551

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: ES963_RS13345
• Genome accession: NZ_CP035390
• Coordinates: 2470370..2472700 (-)
• Length: 776 a.a.
• NCBI ID: WP_046160607.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain SRCM103641
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2465370..2477700

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES963_RS13310 (ES963_13310)	yqxA	2465708..2466046 (-)	339	WP_046160606.1	YqxA family protein	-
ES963_RS13315 (ES963_13315)	spoIIP	2466063..2467268 (-)	1206	WP_014477383.1	spore autolysin SpoIIP	-
ES963_RS13320 (ES963_13320)	gpr	2467331..2468437 (-)	1107	WP_014480309.1	GPR endopeptidase	-
ES963_RS13325 (ES963_13325)	rpsT	2468641..2468907 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
ES963_RS13330 (ES963_13330)	holA	2468922..2469965 (-)	1044	WP_029317888.1	DNA polymerase III subunit delta	-
ES963_RS13335 (ES963_13335)	-	2470005..2470118 (-)	114	WP_122060479.1	hypothetical protein	-
ES963_RS13340 (ES963_13340)	yqzM	2470195..2470329 (+)	135	WP_003229983.1	YqzM family protein	-
ES963_RS13345 (ES963_13345)	comEC	2470370..2472700 (-)	2331	WP_046160607.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ES963_RS13350 (ES963_13350)	comEB	2472704..2473273 (-)	570	WP_003229978.1	ComE operon protein 2	-
ES963_RS13355 (ES963_13355)	comEA	2473340..2473957 (-)	618	WP_046160608.1	competence protein ComEA	Machinery gene
ES963_RS13360 (ES963_13360)	comER	2474041..2474862 (+)	822	WP_032726195.1	late competence protein ComER	-
ES963_RS13365 (ES963_13365)	yqeM	2474928..2475671 (-)	744	WP_046160609.1	class I SAM-dependent methyltransferase	-
ES963_RS13370 (ES963_13370)	rsfS	2475668..2476024 (-)	357	WP_014480315.1	ribosome silencing factor	-
ES963_RS13375 (ES963_13375)	yqeK	2476042..2476602 (-)	561	WP_014480316.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
ES963_RS13380 (ES963_13380)	nadD	2476592..2477161 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
ES963_RS13385 (ES963_13385)	yhbY	2477173..2477463 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86846.48 Da
• Isoelectric Point: 7.2477

>NTDB_id=339551 ES963_RS13345 WP_046160607.1 2470370..2472700(-) (comEC) [Bacillus subtilis strain SRCM103641]
MRNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDTIPKIDGDRMSMMVKTPDKEKWAAAYRIQSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPDSAGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVHSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFHQVKTSLRQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWTNRLITNIADVEVFTIMIAHPAPVLLFLFTVTIILLLMAIEKRSLSQLMVTGG
ICCTVMFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAEILLKYHKVKRLVIPKGFVSEPKDEKVLQAAREEGVEIEEVKRGDVLQIKDLQFHVLSPE
APDPASKNNSSLVLWMETGGMSWILTGDLEKEGEQEVMNVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKN
NRYHHPHQEVLQLLQRHSIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=339551 ES963_RS13345 WP_046160607.1 2470370..2472700(-) (comEC) [Bacillus subtilis strain SRCM103641]
ATGCGTAATTCGCGTTTGTTATTGCCTATGGCGGCAGCTTCGGCAACGGCTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTTATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACCTATCAATTC
AAGGCAGTGATTGACACTATTCCCAAAATTGACGGCGACCGTATGTCTATGATGGTTAAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCAGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAATCACGCAACTGTGCCGGGTGCATTTGATTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAATTACTCTGTCACGTCTATCCAAAACTGCAGCGAACCTGAAAATTTTAAGTACAAGGTGCTCAGCTTGAGAAA
ACATATCATATCATTCACAAACAGCCTTCTGCCTCCTGATTCGGCAGGAATTGTACAGGCACTTACAGTCGGTGACAGAT
TTTATGTGGAGGACGAAGTGCTTACCGCGTATCAAAAGCTTGGTGTTGTCCATCTCTTGGCGATATCAGGACTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATGATCCGTCTTGGTATAACAAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGCCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGTCTTTCATACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCATCA
GGTTAAAACCTCTTTGAGGCAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTCCTATATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GACCAATAGGCTAATCACAAACATTGCAGATGTTGAAGTGTTCACGATTATGATCGCACATCCTGCACCTGTTTTGCTTT
TTTTATTCACGGTCACGATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGGTAACCGGAGGC
ATTTGCTGCACGGTGATGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGTCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAGCAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGATTCTGCTGAAGTATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGGCAGCCAGGGAAG
AGGGAGTGGAAATTGAAGAGGTGAAGCGAGGCGATGTGTTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCGGAA
GCACCTGATCCGGCAAGCAAAAATAATTCATCTCTCGTTCTTTGGATGGAGACGGGCGGTATGAGCTGGATCTTGACGGG
TGATCTGGAGAAAGAAGGGGAACAAGAGGTGATGAACGTGTTTCCGAATATAAAAGCAGATGTGTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGGAAAAAC
AATCGGTACCATCATCCTCATCAAGAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGACCAAAA
CGGAACGATCCAATATAGATATAAAAACAGAGTTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

• Competence protein (Competence) (208-469)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	98.711	100	0.987