Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   VC395_RS13525 Genome accession   NC_012582
Coordinates   2867551..2868183 (+) Length   210 a.a.
NCBI ID   WP_000242748.1    Uniprot ID   O34015
Organism   Vibrio cholerae O395     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2862551..2873183
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VC395_RS13500 (VC395_2721) - 2862616..2864532 (+) 1917 WP_000627681.1 ABC transporter ATP-binding protein -
  VC395_RS13505 (VC395_2722) - 2864533..2865018 (+) 486 WP_001278735.1 TIGR02444 family protein -
  VC395_RS13510 (VC395_2723) - 2865015..2866004 (+) 990 WP_000627575.1 hydrolase -
  VC395_RS13515 (VC395_2725) - 2866133..2866342 (+) 210 WP_000586561.1 YheU family protein -
  VC395_RS13520 (VC395_2726) - 2866439..2867308 (+) 870 WP_001274667.1 phosphoribulokinase -
  VC395_RS13525 (VC395_2727) crp 2867551..2868183 (+) 633 WP_000242748.1 cAMP-activated global transcriptional regulator CRP Regulator
  VC395_RS13530 (VC395_2728) - 2868262..2869053 (-) 792 WP_000189091.1 DUF1338 domain-containing protein -
  VC395_RS13535 (VC395_2729) astD 2869196..2870653 (-) 1458 WP_000150128.1 succinylglutamate-semialdehyde dehydrogenase -
  VC395_RS13540 (VC395_2730) astA 2870663..2871682 (-) 1020 WP_000962042.1 arginine N-succinyltransferase -
  VC395_RS13545 (VC395_2731) - 2871822..2873033 (-) 1212 WP_000215482.1 aspartate aminotransferase family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23667.51 Da        Isoelectric Point: 8.2784

>NTDB_id=33935 VC395_RS13525 WP_000242748.1 2867551..2868183(+) (crp) [Vibrio cholerae O395]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERTAWVRAKTPCEVAEISFKKFRQLIQVNPDILMRLSGQMARRLQMTSQKVGDLAFLDVTGRIAQTLLNLARQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=33935 VC395_RS13525 WP_000242748.1 2867551..2868183(+) (crp) [Vibrio cholerae O395]
ATGGTTCTAGGTAAACCTCAAACCGATCCAACACTAGAGTGGTTTCTTTCACATTGTCACATTCATAAGTACCCATCAAA
AAGCACGCTGATCCACGCGGGTGAGAAGGCGGAAACGCTGTACTACATCGTAAAAGGTTCAGTTGCGGTACTGATCAAAG
ATGAAGAAGGTAAAGAGATGATTCTCTCTTACCTGAACCAAGGTGATTTCATCGGTGAACTCGGCCTGTTTGAAGAAGGT
CAAGAGCGTACCGCTTGGGTTCGTGCCAAAACACCGTGTGAAGTGGCTGAAATCTCATTTAAGAAATTCCGTCAGTTAAT
CCAAGTTAACCCAGACATTTTGATGCGCCTTTCAGGTCAAATGGCTCGTCGTCTGCAAATGACCAGCCAGAAAGTTGGCG
ACCTTGCGTTCCTAGACGTAACTGGCCGTATCGCACAGACTCTGCTGAATCTTGCACGTCAGCCAGATGCGATGACTCAC
CCTGACGGTATGCAAATCAAGATCACTCGCCAAGAGATCGGTCAAATTGTTGGCTGTTCTCGCGAAACCGTTGGCCGCAT
CCTCAAGATGCTGGAAGAGCAGAACCTGATCTCTGCCCACGGTAAAACCATCGTGGTTTACGGCACTCGCTAA

Domains

Predicted by InterproScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O34015

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

99.524

100

0.995
  crp Haemophilus influenzae Rd KW20

75.49

97.143

0.733
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment