Detailed information NTG0338723

Bioinformatically predicted

Overview

• Name: comGG/cglG
• Type: Machinery gene
• Locus tag: EQH15_RS09675
• Genome accession: NZ_CP035265
• Coordinates: 1872004..1872417 (-)
• Length: 137 a.a.
• NCBI ID: WP_000265622.1
• Uniprot ID: Q8CY84
• Organism: Streptococcus pneumoniae strain TVO_1901920
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1867004..1877417

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH15_RS09650 (EQH15_10145)	-	1867699..1868523 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
EQH15_RS09655 (EQH15_10150)	rnpA	1868498..1868869 (-)	372	WP_000739239.1	ribonuclease P protein component	-
EQH15_RS10875	-	1868886..1869017 (-)	132	WP_000768904.1	hypothetical protein	-
EQH15_RS09660 (EQH15_10155)	-	1869018..1870208 (-)	1191	WP_000167766.1	acetate kinase	-
EQH15_RS09665 (EQH15_10160)	comYH	1870259..1871212 (-)	954	WP_000345122.1	class I SAM-dependent methyltransferase	Machinery gene
EQH15_RS09670 (EQH15_10165)	-	1871273..1871867 (-)	595	Protein_1902	class I SAM-dependent methyltransferase	-
EQH15_RS09675 (EQH15_10170)	comGG/cglG	1872004..1872417 (-)	414	WP_000265622.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQH15_RS09680 (EQH15_10175)	comGF/cglF	1872395..1872856 (-)	462	WP_000250534.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQH15_RS09685 (EQH15_10180)	comGE/cglE	1872819..1873121 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQH15_RS09690 (EQH15_10185)	comGD/cglD	1873084..1873488 (-)	405	WP_000588026.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQH15_RS09695 (EQH15_10190)	comGC/cglC	1873481..1873807 (-)	327	WP_000738626.1	comG operon protein ComGC	Machinery gene
EQH15_RS09700 (EQH15_10195)	comGB/cglB	1873809..1874825 (-)	1017	WP_074196785.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQH15_RS09705 (EQH15_10200)	comGA/cglA/cilD	1874773..1875714 (-)	942	WP_000249564.1	competence type IV pilus ATPase ComGA	Machinery gene
EQH15_RS09710 (EQH15_10205)	-	1875790..1876155 (-)	366	WP_000286415.1	DUF1033 family protein	-
EQH15_RS09715 (EQH15_10210)	-	1876306..1877364 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 137 a.a.
• Molecular weight: 16003.46 Da
• Isoelectric Point: 10.2472

>NTDB_id=338723 EQH15_RS09675 WP_000265622.1 1872004..1872417(-) (comGG/cglG) [Streptococcus pneumoniae strain TVO_1901920]
MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNKEKLVAFAMAKRTKDKVEQESGEQFFNLGQVSYQNKK
TGLVTRVRTDKSQYEFLFPSVKIKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS

Nucleotide

• Length: 414 bp

>NTDB_id=338723 EQH15_RS09675 WP_000265622.1 1872004..1872417(-) (comGG/cglG) [Streptococcus pneumoniae strain TVO_1901920]
GTGTGGAAAAAGAAAAAAGTTAAGGCAGGTGTTCTCCTCTACGCAGTCACCATAGCAGCCATCTTTAGTCTTTTGTTGCA
ATTTTATTTGAACCGACAAGTCGCCCACTATCAAGACTATGCTTTGAATAAAGAAAAATTGGTTGCTTTTGCTATGGCTA
AACGAACCAAAGATAAGGTTGAGCAAGAAAGTGGGGAACAGTTTTTTAATCTAGGTCAGGTAAGCTATCAAAACAAGAAA
ACTGGCTTAGTGACGAGGGTTCGTACGGATAAGAGCCAATATGAGTTTCTGTTTCCTTCAGTCAAAATCAAAGAAGAGAA
AAGAGATAAAAAGGAAGAGGTAGCGACCGATTCAAGCGAAAAAGTGGAGAAGAAAAAATCAGAAGAGAAGCCTGAAAAGA
AAGAGAATTCATAG

Domains

No domain identified.

3D structure

• AlphaFold DB: Q8CY84

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGG/cglG	Streptococcus pneumoniae Rx1	100	100	1
comGG/cglG	Streptococcus pneumoniae D39	100	100	1
comGG/cglG	Streptococcus pneumoniae R6	100	100	1
comGG/cglG	Streptococcus pneumoniae TIGR4	100	100	1
comGG/cglG	Streptococcus mitis SK321	87.591	100	0.876
comGG/cglG	Streptococcus mitis NCTC 12261	89.256	88.321	0.788
comYG	Streptococcus mutans UA140	38.806	97.81	0.38
comYG	Streptococcus mutans UA159	38.806	97.81	0.38