Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   EQH15_RS09665 Genome accession   NZ_CP035265
Coordinates   1870259..1871212 (-) Length   317 a.a.
NCBI ID   WP_000345122.1    Uniprot ID   A0A0I7TJC1
Organism   Streptococcus pneumoniae strain TVO_1901920     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1865259..1876212
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH15_RS09640 (EQH15_10135) - 1866020..1866643 (-) 624 WP_000932660.1 hypothetical protein -
  EQH15_RS09645 (EQH15_10140) jag 1866694..1867680 (-) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  EQH15_RS09650 (EQH15_10145) - 1867699..1868523 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  EQH15_RS09655 (EQH15_10150) rnpA 1868498..1868869 (-) 372 WP_000739239.1 ribonuclease P protein component -
  EQH15_RS10875 - 1868886..1869017 (-) 132 WP_000768904.1 hypothetical protein -
  EQH15_RS09660 (EQH15_10155) - 1869018..1870208 (-) 1191 WP_000167766.1 acetate kinase -
  EQH15_RS09665 (EQH15_10160) comYH 1870259..1871212 (-) 954 WP_000345122.1 class I SAM-dependent methyltransferase Machinery gene
  EQH15_RS09670 (EQH15_10165) - 1871273..1871867 (-) 595 Protein_1902 class I SAM-dependent methyltransferase -
  EQH15_RS09675 (EQH15_10170) comGG/cglG 1872004..1872417 (-) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH15_RS09680 (EQH15_10175) comGF/cglF 1872395..1872856 (-) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH15_RS09685 (EQH15_10180) comGE/cglE 1872819..1873121 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH15_RS09690 (EQH15_10185) comGD/cglD 1873084..1873488 (-) 405 WP_000588026.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH15_RS09695 (EQH15_10190) comGC/cglC 1873481..1873807 (-) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  EQH15_RS09700 (EQH15_10195) comGB/cglB 1873809..1874825 (-) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH15_RS09705 (EQH15_10200) comGA/cglA/cilD 1874773..1875714 (-) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH15_RS09710 (EQH15_10205) - 1875790..1876155 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35745.94 Da        Isoelectric Point: 4.2706

>NTDB_id=338722 EQH15_RS09665 WP_000345122.1 1870259..1871212(-) (comYH) [Streptococcus pneumoniae strain TVO_1901920]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSNLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=338722 EQH15_RS09665 WP_000345122.1 1870259..1871212(-) (comYH) [Streptococcus pneumoniae strain TVO_1901920]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTTATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCAGATGCCATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAATGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTAATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0I7TJC1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

53.994

98.738

0.533
  comYH Streptococcus mutans UA159

53.674

98.738

0.53

Multiple sequence alignment