Detailed information NTG0338631

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: F1538_RS05100
• Genome accession: NZ_CP043771
• Coordinates: 1026173..1026847 (-)
• Length: 224 a.a.
• NCBI ID: WP_005647998.1
• Uniprot ID: A0ABY1VSD0
• Organism: Haemophilus influenzae biotype aegyptius strain HE15/F3028
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1021173..1031847

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F1538_RS05075 (F1538_05085)	-	1021173..1021571 (-)	399	WP_032826358.1	hypothetical protein	-
F1538_RS05080 (F1538_05090)	-	1021582..1023567 (-)	1986	WP_013526171.1	Mu transposase C-terminal domain-containing protein	-
F1538_RS05085 (F1538_05095)	-	1023611..1023889 (-)	279	WP_041174962.1	helix-turn-helix domain-containing protein	-
F1538_RS05090 (F1538_05100)	-	1024065..1024781 (+)	717	WP_013526172.1	S24 family peptidase	-
F1538_RS10180	-	1025162..1025329 (-)	168	WP_158305134.1	hypothetical protein	-
F1538_RS05095 (F1538_05105)	rumB	1025374..1025808 (+)	435	Protein_996	23S rRNA (uracil(747)-C(5))-methyltransferase	-
F1538_RS05100 (F1538_05110)	crp	1026173..1026847 (-)	675	WP_005647998.1	cAMP-activated global transcriptional regulator CRP	Regulator
F1538_RS05105 (F1538_05115)	-	1026832..1027083 (-)	252	WP_005647999.1	YheU family protein	-
F1538_RS05110 (F1538_05120)	slmA	1027105..1027761 (-)	657	WP_005648000.1	nucleoid occlusion factor SlmA	-
F1538_RS05115 (F1538_05125)	dut	1027765..1028220 (-)	456	WP_005631431.1	dUTP diphosphatase	-
F1538_RS05120 (F1538_05130)	coaBC	1028268..1029470 (-)	1203	WP_011272308.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
F1538_RS05125 (F1538_05135)	radC	1029633..1030298 (+)	666	WP_013526173.1	DNA repair protein RadC	Machinery gene
F1538_RS05130 (F1538_05140)	rpmB	1030512..1030748 (+)	237	WP_005542826.1	50S ribosomal protein L28	-
F1538_RS05135 (F1538_05145)	rpmG	1030760..1030930 (+)	171	WP_005613503.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25151.85 Da
• Isoelectric Point: 6.8375

>NTDB_id=338631 F1538_RS05100 WP_005647998.1 1026173..1026847(-) (crp) [Haemophilus influenzae biotype aegyptius strain HE15/F3028]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide

• Length: 675 bp

>NTDB_id=338631 F1538_RS05100 WP_005647998.1 1026173..1026847(-) (crp) [Haemophilus influenzae biotype aegyptius strain HE15/F3028]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGA
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterProScan.

• Cyclic nucleotide-binding domain (cNMP_binding) (36-124)

• Crp-like helix-turn-helix domain (HTH_Crp_2) (156-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Haemophilus influenzae Rd KW20	100	100	1
crp	Vibrio cholerae strain A1552	75.49	91.071	0.687
crp	Acinetobacter baumannii D1279779	48.705	86.161	0.42