Detailed information NTG0338628

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: EQH16_RS08635
• Genome accession: NZ_CP035264
• Coordinates: 1678432..1679091 (+)
• Length: 219 a.a.
• NCBI ID: WP_000565009.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901921
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1673432..1684091

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH16_RS08610 (EQH16_09035)	-	1673738..1674055 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
EQH16_RS08615 (EQH16_09040)	-	1674070..1674966 (-)	897	WP_000825663.1	PEP phosphonomutase	-
EQH16_RS08620 (EQH16_09045)	-	1674969..1676231 (-)	1263	WP_000413345.1	PTS sugar transporter subunit IIC	-
EQH16_RS08625 (EQH16_09050)	-	1676510..1677688 (+)	1179	WP_001866460.1	ROK family transcriptional regulator	-
EQH16_RS08630 (EQH16_09055)	-	1677916..1678362 (-)	447	WP_000155430.1	GNAT family N-acetyltransferase	-
EQH16_RS08635 (EQH16_09060)	cclA/cilC	1678432..1679091 (+)	660	WP_000565009.1	A24 family peptidase	Machinery gene
EQH16_RS08640 (EQH16_09065)	trpA	1679063..1679839 (-)	777	WP_001126996.1	tryptophan synthase subunit alpha	-
EQH16_RS08645 (EQH16_09070)	trpB	1679832..1681055 (-)	1224	WP_000331284.1	tryptophan synthase subunit beta	-
EQH16_RS08650 (EQH16_09075)	-	1681033..1681632 (-)	600	WP_000169914.1	phosphoribosylanthranilate isomerase	-
EQH16_RS08655 (EQH16_09080)	trpC	1681619..1682386 (-)	768	WP_000076566.1	indole-3-glycerol phosphate synthase TrpC	-
EQH16_RS08660 (EQH16_09085)	trpD	1682383..1683387 (-)	1005	WP_000658684.1	anthranilate phosphoribosyltransferase	-
EQH16_RS08665 (EQH16_09090)	-	1683398..1683964 (-)	567	WP_000601927.1	aminodeoxychorismate/anthranilate synthase component II	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24890.08 Da
• Isoelectric Point: 7.8950

>NTDB_id=338628 EQH16_RS08635 WP_000565009.1 1678432..1679091(+) (cclA/cilC) [Streptococcus pneumoniae strain TVO_1901921]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLSQVILITAGLTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLKKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=338628 EQH16_RS08635 WP_000565009.1 1678432..1679091(+) (cclA/cilC) [Streptococcus pneumoniae strain TVO_1901921]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTAGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTCAAGTCATCCTAATCACTGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGAAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae Rx1	98.63	100	0.986
cclA/cilC	Streptococcus pneumoniae D39	98.63	100	0.986
cclA/cilC	Streptococcus pneumoniae R6	98.63	100	0.986
cclA/cilC	Streptococcus pneumoniae TIGR4	95.434	100	0.954
cclA/cilC	Streptococcus mitis SK321	92.237	100	0.922
cclA/cilC	Streptococcus mitis NCTC 12261	86.301	100	0.863