Detailed information NTG0033844

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: VCM66_RS12830
• Genome accession: NC_012578
• Coordinates: 2781163..2782170 (-)
• Length: 335 a.a.
• NCBI ID: WP_000224452.1
• Uniprot ID: A0A085RG68
• Organism: Vibrio cholerae M66-2
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 2776163..2787170

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VCM66_RS12805 (VCM66_2592)	rraA	2776738..2777253 (-)	516	WP_000456236.1	ribonuclease E activity regulator RraA	-
VCM66_RS12810 (VCM66_2593)	-	2777328..2778245 (-)	918	WP_001066162.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
VCM66_RS12815 (VCM66_2594)	hslU	2778349..2779680 (-)	1332	WP_001293365.1	HslU--HslV peptidase ATPase subunit	-
VCM66_RS12820 (VCM66_2595)	hslV	2779746..2780303 (-)	558	WP_000208249.1	ATP-dependent protease subunit HslV	-
VCM66_RS12825 (VCM66_2596)	-	2780440..2780991 (-)	552	WP_001884022.1	SPOR domain-containing protein	-
VCM66_RS12830 (VCM66_2597)	cytR	2781163..2782170 (-)	1008	WP_000224452.1	DNA-binding transcriptional regulator CytR	Regulator
VCM66_RS12835 (VCM66_2598)	priA	2782476..2784680 (-)	2205	WP_001247858.1	primosomal protein N'	-
VCM66_RS12840 (VCM66_2599)	rpmE	2784935..2785153 (+)	219	WP_000643446.1	50S ribosomal protein L31	-
VCM66_RS12845 (VCM66_2601)	-	2785461..2786738 (+)	1278	WP_001278588.1	malic enzyme-like NAD(P)-binding protein	-
VCM66_RS12850 (VCM66_2602)	metJ	2786849..2787166 (-)	318	WP_000796267.1	met regulon transcriptional regulator MetJ	-

Sequence

Protein

• Length: 335 a.a.
• Molecular weight: 37018.59 Da
• Isoelectric Point: 7.0759

>NTDB_id=33844 VCM66_RS12830 WP_000224452.1 2781163..2782170(-) (cytR) [Vibrio cholerae M66-2]
MATMKDVAQLAGVSTATVSRALMNPEKVSSSTRKRVEEAVLEAGYSPNSLARNLRRNESKTIVAIVPDICDPYFSEIIRG
IEDAAMEHGYLVLLGDSGQQKRRENSFVNLVFTKQADGMLLLGTDLPFDVSKPEQKNLPPMVMACEFAPELELPTVHIDN
LTSAFEAVNYLTQLGHKRIAQISGPQHAALCQFRHQGYQQALRRAGITMNPTYCTFGDFTFEAGAKAVRQLLALPEQPTA
IFCHNDTMAIGAIQEAKRLGLRVPQDLSVVGFDDIQFAQYCDPPLTTISQPRYEIGRQAMLMMLELLRGHDVRAGSRLLE
TKLVVRESAAPPSKK

Nucleotide

• Length: 1008 bp

>NTDB_id=33844 VCM66_RS12830 WP_000224452.1 2781163..2782170(-) (cytR) [Vibrio cholerae M66-2]
ATGGCGACAATGAAGGATGTTGCCCAGCTTGCTGGAGTTTCAACCGCGACCGTGTCTCGTGCGTTGATGAATCCAGAGAA
AGTCTCGTCGTCCACTCGTAAACGAGTGGAAGAGGCCGTGCTGGAAGCGGGTTACTCACCCAATTCTTTGGCGCGCAATT
TGCGCCGTAATGAATCGAAAACCATCGTTGCTATCGTGCCAGATATCTGTGATCCCTACTTTTCTGAGATCATTCGCGGT
ATTGAAGATGCCGCGATGGAGCACGGTTATCTGGTGCTGTTGGGGGATAGTGGTCAACAGAAGCGTCGGGAGAACTCGTT
CGTTAATCTGGTGTTTACCAAACAGGCAGACGGTATGTTGCTGCTGGGGACAGATTTGCCGTTTGATGTGAGTAAACCTG
AGCAGAAAAACCTACCGCCTATGGTGATGGCGTGTGAATTTGCGCCAGAGCTGGAATTGCCAACGGTACACATTGATAAC
CTGACCTCGGCATTTGAGGCGGTAAACTATCTCACTCAGCTTGGGCACAAACGGATTGCGCAGATCTCAGGTCCACAACA
TGCTGCGCTGTGCCAATTCCGTCATCAAGGCTATCAACAGGCGTTGCGTCGTGCTGGCATCACCATGAACCCGACTTACT
GCACTTTTGGCGATTTCACTTTTGAAGCCGGGGCAAAAGCGGTGCGTCAGCTGTTGGCATTGCCTGAGCAGCCGACCGCG
ATTTTCTGTCATAACGATACGATGGCGATTGGCGCAATTCAGGAAGCGAAGCGACTTGGCTTGCGCGTACCGCAAGATCT
CTCTGTGGTCGGTTTTGACGATATTCAGTTTGCCCAGTACTGCGATCCCCCATTAACCACCATTTCGCAGCCGCGTTATG
AGATTGGCCGTCAAGCCATGCTGATGATGCTTGAGCTGCTTCGCGGACACGATGTACGTGCTGGATCGCGTCTTTTGGAG
ACCAAGCTGGTCGTGCGTGAGAGTGCTGCGCCGCCAAGCAAGAAGTAA

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (3-48)

• Periplasmic binding protein-like domain (Peripla_BP_3) (168-328)

3D structure

• AlphaFold DB: A0A085RG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio cholerae C6706	100	100	1
cytR	Vibrio parahaemolyticus RIMD 2210633	90.719	99.701	0.904