Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   EQH19_RS08345 Genome accession   NZ_CP035261
Coordinates   1656000..1656659 (+) Length   219 a.a.
NCBI ID   WP_000565014.1    Uniprot ID   A0A4U1IZ10
Organism   Streptococcus pneumoniae strain TVO_1901924     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1651000..1661659
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH19_RS08320 (EQH19_08815) - 1651305..1651622 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  EQH19_RS08325 (EQH19_08820) - 1651637..1652533 (-) 897 WP_000825665.1 PEP phosphonomutase -
  EQH19_RS08330 (EQH19_08825) - 1652536..1653798 (-) 1263 WP_000413336.1 PTS sugar transporter subunit IIC -
  EQH19_RS08335 (EQH19_08830) - 1654078..1655256 (+) 1179 WP_000175876.1 ROK family transcriptional regulator -
  EQH19_RS08340 (EQH19_08835) - 1655484..1655930 (-) 447 WP_000155401.1 GNAT family N-acetyltransferase -
  EQH19_RS08345 (EQH19_08840) cclA/cilC 1656000..1656659 (+) 660 WP_000565014.1 A24 family peptidase Machinery gene
  EQH19_RS08350 (EQH19_08845) - 1656711..1657862 (-) 1152 WP_000481756.1 XRE family transcriptional regulator -
  EQH19_RS08355 (EQH19_08850) - 1657877..1658608 (-) 732 WP_000934017.1 hypothetical protein -
  EQH19_RS08360 (EQH19_08855) - 1658828..1658938 (+) 111 Protein_1672 prepilin peptidase -
  EQH19_RS08365 (EQH19_08860) trpA 1658910..1659686 (-) 777 WP_001127015.1 tryptophan synthase subunit alpha -
  EQH19_RS08370 (EQH19_08865) trpB 1659679..1660902 (-) 1224 WP_000331292.1 tryptophan synthase subunit beta -
  EQH19_RS08375 (EQH19_08870) - 1660880..1661479 (-) 600 WP_000169898.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24879.99 Da        Isoelectric Point: 7.6418

>NTDB_id=338394 EQH19_RS08345 WP_000565014.1 1656000..1656659(+) (cclA/cilC) [Streptococcus pneumoniae strain TVO_1901924]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=338394 EQH19_RS08345 WP_000565014.1 1656000..1656659(+) (cclA/cilC) [Streptococcus pneumoniae strain TVO_1901924]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
ATACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATTGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTACTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U1IZ10

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

97.717

100

0.977
  cclA/cilC Streptococcus pneumoniae Rx1

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae D39

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae R6

97.26

100

0.973
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

86.758

100

0.868

Multiple sequence alignment