Detailed information NTG0338379

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: EQH19_RS04640
• Genome accession: NZ_CP035261
• Coordinates: 921190..922143 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain TVO_1901924
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 916190..927143

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH19_RS04615 (EQH19_04910)	rpmG	916933..917082 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
EQH19_RS04620 (EQH19_04915)	secG	917122..917355 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
EQH19_RS04625 (EQH19_04920)	rnr	917457..919811 (+)	2355	WP_000654925.1	ribonuclease R	-
EQH19_RS04630 (EQH19_04925)	smpB	919774..920241 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
EQH19_RS04635 (EQH19_04930)	tehB	920257..921117 (+)	861	WP_000413763.1	SAM-dependent methyltransferase TehB	-
EQH19_RS04640 (EQH19_04935)	coiA	921190..922143 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
EQH19_RS04645 (EQH19_04940)	pepF	922162..923964 (+)	1803	WP_000244144.1	oligoendopeptidase F	Regulator
EQH19_RS04650 (EQH19_04945)	-	923966..924679 (+)	714	WP_000230401.1	O-methyltransferase	-
EQH19_RS04655 (EQH19_04950)	prsA	924746..925687 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
EQH19_RS04660 (EQH19_04955)	-	925806..926147 (-)	342	Protein_931	transposase	-
EQH19_RS04665 (EQH19_04965)	-	926561..926656 (+)	96	Protein_932	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=338379 EQH19_RS04640 WP_000495909.1 921190..922143(+) (coiA) [Streptococcus pneumoniae strain TVO_1901924]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=338379 EQH19_RS04640 WP_000495909.1 921190..922143(+) (coiA) [Streptococcus pneumoniae strain TVO_1901924]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435