Detailed information NTG0338338

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: EQH20_RS09125
• Genome accession: NZ_CP035260
• Coordinates: 1791988..1792290 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901925
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1786988..1797290

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH20_RS09095 (EQH20_09595)	rnpA	1787668..1788039 (-)	372	WP_000739246.1	ribonuclease P protein component	-
EQH20_RS10235	-	1788056..1788187 (-)	132	WP_000768904.1	hypothetical protein	-
EQH20_RS09100 (EQH20_09600)	-	1788188..1789378 (-)	1191	WP_000167766.1	acetate kinase	-
EQH20_RS09105 (EQH20_09605)	comYH	1789429..1790382 (-)	954	WP_000345130.1	class I SAM-dependent methyltransferase	Machinery gene
EQH20_RS09110 (EQH20_09610)	-	1790443..1791037 (-)	595	Protein_1784	class I SAM-dependent methyltransferase	-
EQH20_RS09115 (EQH20_09615)	comGG/cglG	1791140..1791586 (-)	447	WP_061647526.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQH20_RS09120 (EQH20_09620)	comGF/cglF	1791564..1792025 (-)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQH20_RS09125 (EQH20_09625)	comGE/cglE	1791988..1792290 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQH20_RS09130 (EQH20_09630)	comGD/cglD	1792253..1792657 (-)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQH20_RS09135 (EQH20_09635)	comGC/cglC	1792650..1792976 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
EQH20_RS09140 (EQH20_09640)	comGB/cglB	1792978..1793994 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQH20_RS09145 (EQH20_09645)	comGA/cglA/cilD	1793942..1794883 (-)	942	WP_000249552.1	competence type IV pilus ATPase ComGA	Machinery gene
EQH20_RS09150 (EQH20_09650)	-	1794959..1795324 (-)	366	WP_000286415.1	DUF1033 family protein	-
EQH20_RS09155 (EQH20_09655)	-	1795475..1796533 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=338338 EQH20_RS09125 WP_000413382.1 1791988..1792290(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901925]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=338338 EQH20_RS09125 WP_000413382.1 1791988..1792290(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901925]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4