Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   EQH21_RS02455 Genome accession   NZ_CP035259
Coordinates   477806..478543 (+) Length   245 a.a.
NCBI ID   WP_001219121.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901926     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 472806..483543
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH21_RS02425 (EQH21_02560) - 474138..474425 (-) 288 WP_000777761.1 hypothetical protein -
  EQH21_RS02430 (EQH21_02565) - 474435..474845 (-) 411 WP_001112361.1 HIT family protein -
  EQH21_RS02435 (EQH21_02570) pptA 474913..475644 (+) 732 WP_000889923.1 ABC transporter ATP-binding protein Regulator
  EQH21_RS02440 (EQH21_02575) - 475641..476690 (+) 1050 WP_000653767.1 ABC transporter permease -
  EQH21_RS02445 (EQH21_02580) - 476858..477187 (-) 330 WP_000132575.1 hypothetical protein -
  EQH21_RS02450 (EQH21_02585) - 477463..477801 (+) 339 WP_000682120.1 LytTR family DNA-binding domain-containing protein -
  EQH21_RS02455 (EQH21_02590) comE/blpR 477806..478543 (+) 738 WP_001219121.1 response regulator transcription factor Regulator
  EQH21_RS02460 (EQH21_02595) - 478557..479897 (+) 1341 WP_001028653.1 sensor histidine kinase -
  EQH21_RS02465 (EQH21_02600) blpC 479942..480097 (-) 156 WP_000358810.1 quorum-sensing system pheromone BlpC -
  EQH21_RS02470 (EQH21_02605) - 480154..481515 (-) 1362 WP_001069085.1 bacteriocin secretion accessory protein -
  EQH21_RS10700 comA/nlmT 481526..482437 (-) 912 WP_001828567.1 ATP-binding cassette domain-containing protein Regulator
  EQH21_RS10705 blpA 482426..483150 (-) 725 Protein_495 peptide cleavage/export ABC transporter BlpA -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28740.91 Da        Isoelectric Point: 6.4140

>NTDB_id=338215 EQH21_RS02455 WP_001219121.1 477806..478543(+) (comE/blpR) [Streptococcus pneumoniae strain TVO_1901926]
MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=338215 EQH21_RS02455 WP_001219121.1 477806..478543(+) (comE/blpR) [Streptococcus pneumoniae strain TVO_1901926]
ATGAGAATATTTGTTTTAGAGGATGATTTTTCCCAACAGACTAGAATTGAAACGACGATTGAGAAACTTTTGAAAGCACA
TCATATCATTCCTAGCTCTTTTGAGGTATTTGGCAAGCCGGACCAACTGCTGGCTGAAGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAAGAGATGAAGGGACTGGAAGTGGCTAGAAAGATTCGGGATCGGGAT
CCTTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTCTGGA
CTATATTGATAAGGCCCTTTCGGCAGAGGAGTTTGAATCTCGAATCGAGACAGCCCTCCTCTATGCCAATAGTCAAGATA
GTAAAAGTCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCCCAATTCCAATATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCTCCCAGAGCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTTTAGAGGA
GGTTTTCAAGCAGGAACCCCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCAAATGTGGTGCATTTGGATA
AGAAAGAAAAACTCCTTTTTTTTCCCAATGGTGGAAGTTGTCTGATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

54.321

99.184

0.539
  comE/comE1 Streptococcus equinus JB1

43.46

96.735

0.42
  comE/comE2 Streptococcus equinus JB1

38.43

98.776

0.38

Multiple sequence alignment