Detailed information NTG0338146

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: EQH22_RS04520
• Genome accession: NZ_CP035258
• Coordinates: 896707..897660 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain TVO_1901927
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 891707..902660

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH22_RS04495 (EQH22_04760)	rpmG	892450..892599 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
EQH22_RS04500 (EQH22_04765)	secG	892639..892872 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
EQH22_RS04505 (EQH22_04770)	rnr	892974..895328 (+)	2355	WP_000654886.1	ribonuclease R	-
EQH22_RS04510 (EQH22_04775)	smpB	895291..895758 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
EQH22_RS04515 (EQH22_04780)	tehB	895774..896634 (+)	861	WP_000413757.1	SAM-dependent methyltransferase TehB	-
EQH22_RS04520 (EQH22_04785)	coiA	896707..897660 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
EQH22_RS04525 (EQH22_04790)	pepF	897679..899490 (+)	1812	WP_000244160.1	oligoendopeptidase F	Regulator
EQH22_RS04530 (EQH22_04795)	-	899492..900205 (+)	714	WP_000230399.1	O-methyltransferase	-
EQH22_RS04535 (EQH22_04800)	prsA	900272..901213 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
EQH22_RS04540 (EQH22_04805)	-	901330..901671 (-)	342	Protein_914	transposase	-
EQH22_RS04545 (EQH22_04815)	-	902084..902179 (+)	96	Protein_915	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=338146 EQH22_RS04520 WP_000495909.1 896707..897660(+) (coiA) [Streptococcus pneumoniae strain TVO_1901927]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=338146 EQH22_RS04520 WP_000495909.1 896707..897660(+) (coiA) [Streptococcus pneumoniae strain TVO_1901927]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTAAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435