Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   EQH22_RS00240 Genome accession   NZ_CP035258
Coordinates   38554..38790 (+) Length   78 a.a.
NCBI ID   WP_000939545.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901927     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 36595..38237 38554..38790 flank 317


Gene organization within MGE regions


Location: 36595..38790
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH22_RS00230 (EQH22_00225) - 36595..37441 (+) 847 Protein_40 IS630 family transposase -
  EQH22_RS00235 (EQH22_00230) - 37501..38288 (-) 788 Protein_41 transposase -
  EQH22_RS00240 (EQH22_00235) comW 38554..38790 (+) 237 WP_000939545.1 sigma(X)-activator ComW Regulator

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9658.13 Da        Isoelectric Point: 6.7051

>NTDB_id=338127 EQH22_RS00240 WP_000939545.1 38554..38790(+) (comW) [Streptococcus pneumoniae strain TVO_1901927]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=338127 EQH22_RS00240 WP_000939545.1 38554..38790(+) (comW) [Streptococcus pneumoniae strain TVO_1901927]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAAGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

100

100

1
  comW Streptococcus pneumoniae D39

100

100

1
  comW Streptococcus pneumoniae R6

100

100

1
  comW Streptococcus pneumoniae TIGR4

100

100

1
  comW Streptococcus mitis SK321

75.641

100

0.756
  comW Streptococcus mitis NCTC 12261

75.325

98.718

0.744

Multiple sequence alignment