Detailed information NTG0338085

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: EQH23_RS08705
• Genome accession: NZ_CP035257
• Coordinates: 1721914..1722573 (+)
• Length: 219 a.a.
• NCBI ID: WP_000564991.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901928
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1716914..1727573

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH23_RS08680 (EQH23_09185)	-	1717219..1717536 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
EQH23_RS08685 (EQH23_09190)	-	1717551..1718447 (-)	897	WP_000825665.1	PEP phosphonomutase	-
EQH23_RS08690 (EQH23_09195)	-	1718444..1719712 (-)	1269	WP_000413337.1	PTS sugar transporter subunit IIC	-
EQH23_RS08695 (EQH23_09200)	-	1719992..1721170 (+)	1179	WP_000175879.1	ROK family transcriptional regulator	-
EQH23_RS08700 (EQH23_09205)	-	1721398..1721844 (-)	447	WP_000155412.1	GNAT family N-acetyltransferase	-
EQH23_RS08705 (EQH23_09210)	cclA/cilC	1721914..1722573 (+)	660	WP_000564991.1	A24 family peptidase	Machinery gene
EQH23_RS08710 (EQH23_09215)	-	1722625..1723776 (-)	1152	WP_000481750.1	ImmA/IrrE family metallo-endopeptidase	-
EQH23_RS08715 (EQH23_09220)	-	1723791..1724522 (-)	732	WP_000934018.1	hypothetical protein	-
EQH23_RS08720 (EQH23_09225)	-	1724748..1724852 (+)	105	Protein_1748	prepilin peptidase	-
EQH23_RS08725 (EQH23_09230)	trpA	1724824..1725600 (-)	777	WP_001127044.1	tryptophan synthase subunit alpha	-
EQH23_RS08730 (EQH23_09235)	trpB	1725593..1726816 (-)	1224	WP_000331294.1	tryptophan synthase subunit beta	-
EQH23_RS08735 (EQH23_09240)	-	1726794..1727393 (-)	600	WP_000169912.1	phosphoribosylanthranilate isomerase	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24880.03 Da
• Isoelectric Point: 7.9671

>NTDB_id=338085 EQH23_RS08705 WP_000564991.1 1721914..1722573(+) (cclA/cilC) [Streptococcus pneumoniae strain TVO_1901928]
MIDFYFFLVGSILASFLGLVIDRFPEKSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=338085 EQH23_RS08705 WP_000564991.1 1721914..1722573(+) (cclA/cilC) [Streptococcus pneumoniae strain TVO_1901928]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGAA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGAGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTATCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae Rx1	95.434	100	0.954
cclA/cilC	Streptococcus pneumoniae D39	95.434	100	0.954
cclA/cilC	Streptococcus pneumoniae R6	95.434	100	0.954
cclA/cilC	Streptococcus mitis SK321	91.781	100	0.918
cclA/cilC	Streptococcus mitis NCTC 12261	85.388	100	0.854