Detailed information NTG0338004

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: EQH24_RS08945
• Genome accession: NZ_CP035256
• Coordinates: 1747034..1747693 (+)
• Length: 219 a.a.
• NCBI ID: WP_000565027.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901930
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1742034..1752693

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH24_RS08920 (EQH24_09370)	-	1742339..1742656 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
EQH24_RS08925 (EQH24_09375)	-	1742671..1743567 (-)	897	WP_000825667.1	PEP phosphonomutase	-
EQH24_RS08930 (EQH24_09380)	-	1743570..1744832 (-)	1263	WP_023396417.1	PTS sugar transporter subunit IIC	-
EQH24_RS08935 (EQH24_09385)	-	1745112..1746290 (+)	1179	WP_000175880.1	ROK family transcriptional regulator	-
EQH24_RS08940 (EQH24_09390)	-	1746518..1746964 (-)	447	WP_000155408.1	GNAT family N-acetyltransferase	-
EQH24_RS08945 (EQH24_09395)	cclA/cilC	1747034..1747693 (+)	660	WP_000565027.1	A24 family peptidase	Machinery gene
EQH24_RS08950 (EQH24_09400)	trpA	1747665..1748441 (-)	777	WP_001126993.1	tryptophan synthase subunit alpha	-
EQH24_RS08955 (EQH24_09405)	trpB	1748434..1749657 (-)	1224	WP_000331298.1	tryptophan synthase subunit beta	-
EQH24_RS08960 (EQH24_09410)	-	1749635..1750234 (-)	600	WP_000169872.1	phosphoribosylanthranilate isomerase	-
EQH24_RS08965 (EQH24_09415)	trpC	1750221..1750988 (-)	768	WP_000076545.1	indole-3-glycerol phosphate synthase TrpC	-
EQH24_RS08970 (EQH24_09420)	trpD	1750985..1751989 (-)	1005	WP_000658684.1	anthranilate phosphoribosyltransferase	-
EQH24_RS08975 (EQH24_09425)	-	1752000..1752566 (-)	567	WP_000601921.1	aminodeoxychorismate/anthranilate synthase component II	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24855.00 Da
• Isoelectric Point: 7.2564

>NTDB_id=338004 EQH24_RS08945 WP_000565027.1 1747034..1747693(+) (cclA/cilC) [Streptococcus pneumoniae strain TVO_1901930]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSVSHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=338004 EQH24_RS08945 WP_000565027.1 1747034..1747693(+) (cclA/cilC) [Streptococcus pneumoniae strain TVO_1901930]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGTCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAGTTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae Rx1	97.26	100	0.973
cclA/cilC	Streptococcus pneumoniae D39	97.26	100	0.973
cclA/cilC	Streptococcus pneumoniae R6	97.26	100	0.973
cclA/cilC	Streptococcus pneumoniae TIGR4	96.804	100	0.968
cclA/cilC	Streptococcus mitis SK321	91.781	100	0.918
cclA/cilC	Streptococcus mitis NCTC 12261	85.845	100	0.858