Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   EQH24_RS02765 Genome accession   NZ_CP035256
Coordinates   535060..535797 (+) Length   245 a.a.
NCBI ID   WP_023396586.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901930     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 530060..540797
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH24_RS02735 (EQH24_02890) - 531392..531679 (-) 288 WP_000777760.1 hypothetical protein -
  EQH24_RS02740 (EQH24_02895) - 531689..532099 (-) 411 WP_001278301.1 HIT family protein -
  EQH24_RS02745 (EQH24_02900) pptA 532167..532898 (+) 732 WP_000889919.1 ABC transporter ATP-binding protein Regulator
  EQH24_RS02750 (EQH24_02905) - 532895..533944 (+) 1050 WP_023396177.1 ABC transporter permease -
  EQH24_RS02755 (EQH24_02915) - 534112..534441 (-) 330 WP_000132572.1 hypothetical protein -
  EQH24_RS02760 (EQH24_02920) - 534717..535055 (+) 339 WP_000876676.1 LytTR family DNA-binding domain-containing protein -
  EQH24_RS02765 (EQH24_02925) comE/blpR 535060..535797 (+) 738 WP_023396586.1 response regulator transcription factor Regulator
  EQH24_RS02770 (EQH24_02930) - 535811..537151 (+) 1341 WP_001028044.1 sensor histidine kinase -
  EQH24_RS02775 (EQH24_02935) blpC 537193..537348 (-) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  EQH24_RS02780 (EQH24_02940) - 537405..538766 (-) 1362 Protein_555 bacteriocin secretion accessory protein -
  EQH24_RS02785 (EQH24_02945) comA/nlmT 538777..540453 (-) 1677 WP_196299874.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28775.88 Da        Isoelectric Point: 5.8326

>NTDB_id=337976 EQH24_RS02765 WP_023396586.1 535060..535797(+) (comE/blpR) [Streptococcus pneumoniae strain TVO_1901930]
MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSTEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIACYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=337976 EQH24_RS02765 WP_023396586.1 535060..535797(+) (comE/blpR) [Streptococcus pneumoniae strain TVO_1901930]
ATGAGAATATTTGTTTTAGAGGATGATTTTTCCCAACAGACTAGGATTGAAACGACGATTGAGAAACTCTTGAAGGAACA
TCATATCACTCCCAGCTCTTTTGAGGTATTTGGCAAGCCAGACCAACTGCTGGCAGAGGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAGGAGATGAAGGGGCTGGAAGTGGCTAGAAAGATTCGGGAACAAGAC
CCCTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTCTGGA
CTATATTGATAAGGCCCTTTCGACAGAGGAGTTTGAATCTCGAATCGAGACAGCCCTCCTCTATGCCAATAGTCAAGATA
GTAAAAGTCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCCCAATTTCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACATCCCCAAGACCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTTTAGAGGA
GGTTTTCAAGCAGGAACCCCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCAAATGTGGTGCATTTGGATA
AGAAAGAAAAACTCCTTTTCTTTCCCAATGGTGGAAGTTGTCTGATCGCGTGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-241)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.909

99.184

0.535
  comE/comE1 Streptococcus equinus JB1

43.46

96.735

0.42
  comE/comE2 Streptococcus equinus JB1

38.43

98.776

0.38

Multiple sequence alignment