Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   EQH26_RS08435 Genome accession   NZ_CP035254
Coordinates   1679331..1679990 (+) Length   219 a.a.
NCBI ID   WP_000565607.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901932     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1674331..1684990
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH26_RS08415 (EQH26_08895) - 1674968..1675864 (-) 897 WP_000825665.1 PEP phosphonomutase -
  EQH26_RS08420 (EQH26_08900) - 1675867..1677129 (-) 1263 WP_000413334.1 PTS sugar transporter subunit IIC -
  EQH26_RS08425 (EQH26_08905) - 1677409..1678587 (+) 1179 WP_000175874.1 ROK family transcriptional regulator -
  EQH26_RS08430 (EQH26_08910) - 1678815..1679261 (-) 447 WP_000155419.1 N-acetyltransferase -
  EQH26_RS08435 (EQH26_08915) cclA/cilC 1679331..1679990 (+) 660 WP_000565607.1 A24 family peptidase Machinery gene
  EQH26_RS08440 (EQH26_08920) - 1680042..1681193 (-) 1152 WP_238126561.1 XRE family transcriptional regulator -
  EQH26_RS08445 (EQH26_08925) - 1681208..1681939 (-) 732 WP_000934017.1 hypothetical protein -
  EQH26_RS08450 (EQH26_08930) - 1682159..1682269 (+) 111 Protein_1695 prepilin peptidase -
  EQH26_RS08455 (EQH26_08935) trpA 1682241..1683017 (-) 777 WP_001126993.1 tryptophan synthase subunit alpha -
  EQH26_RS08460 (EQH26_08940) trpB 1683010..1684233 (-) 1224 WP_000331283.1 tryptophan synthase subunit beta -
  EQH26_RS08465 (EQH26_08945) - 1684211..1684810 (-) 600 WP_054369631.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24826.93 Da        Isoelectric Point: 7.3241

>NTDB_id=337923 EQH26_RS08435 WP_000565607.1 1679331..1679990(+) (cclA/cilC) [Streptococcus pneumoniae strain TVO_1901932]
MIDIYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLHPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=337923 EQH26_RS08435 WP_000565607.1 1679331..1679990(+) (cclA/cilC) [Streptococcus pneumoniae strain TVO_1901932]
ATGATTGATATTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCATCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae Rx1

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae D39

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae R6

96.347

100

0.963
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

86.758

100

0.868

Multiple sequence alignment