Detailed information NTG0337782

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: EQH29_RS09535
• Genome accession: NZ_CP035251
• Coordinates: 1892239..1892700 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250530.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901935
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1887239..1897700

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH29_RS09505 (EQH29_10080)	-	1887544..1888368 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
EQH29_RS09510 (EQH29_10085)	rnpA	1888343..1888714 (-)	372	WP_000739246.1	ribonuclease P protein component	-
EQH29_RS10640	-	1888731..1888862 (-)	132	WP_000768904.1	hypothetical protein	-
EQH29_RS09515 (EQH29_10090)	-	1888863..1890053 (-)	1191	WP_000167766.1	acetate kinase	-
EQH29_RS09520 (EQH29_10095)	comYH	1890104..1891057 (-)	954	WP_000345117.1	class I SAM-dependent methyltransferase	Machinery gene
EQH29_RS09525 (EQH29_10100)	-	1891118..1891711 (-)	594	Protein_1871	class I SAM-dependent methyltransferase	-
EQH29_RS09530 (EQH29_10105)	comGG/cglG	1891848..1892261 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQH29_RS09535 (EQH29_10110)	comGF/cglF	1892239..1892700 (-)	462	WP_000250530.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQH29_RS09540 (EQH29_10115)	comGE/cglE	1892663..1892965 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQH29_RS09545 (EQH29_10120)	comGD/cglD	1892928..1893332 (-)	405	WP_000588006.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQH29_RS09550 (EQH29_10125)	comGC/cglC	1893325..1893651 (-)	327	WP_000738638.1	comG operon protein ComGC	Machinery gene
EQH29_RS09555 (EQH29_10130)	comGB/cglB	1893653..1894669 (-)	1017	WP_075270915.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQH29_RS09560 (EQH29_10135)	comGA/cglA/cilD	1894617..1895558 (-)	942	WP_000249556.1	competence type IV pilus ATPase ComGA	Machinery gene
EQH29_RS09565 (EQH29_10140)	-	1895633..1895998 (-)	366	WP_000286415.1	DUF1033 family protein	-
EQH29_RS09570 (EQH29_10145)	-	1896149..1897207 (-)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17883.39 Da
• Isoelectric Point: 6.4832

>NTDB_id=337782 EQH29_RS09535 WP_000250530.1 1892239..1892700(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901935]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RFYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=337782 EQH29_RS09535 WP_000250530.1 1892239..1892700(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901935]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTGGAAGGCAAT
CGTTTCTATATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae D39	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae R6	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae TIGR4	94.771	100	0.948
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915