Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   EQH31_RS08640 Genome accession   NZ_CP035249
Coordinates   1703205..1703864 (+) Length   219 a.a.
NCBI ID   WP_000565002.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901938     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1698205..1708864
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH31_RS08620 (EQH31_09140) - 1698842..1699738 (-) 897 WP_000825669.1 PEP phosphonomutase -
  EQH31_RS08625 (EQH31_09145) - 1699741..1701003 (-) 1263 WP_000413343.1 PTS sugar transporter subunit IIC -
  EQH31_RS08630 (EQH31_09150) - 1701283..1702461 (+) 1179 WP_000175876.1 ROK family transcriptional regulator -
  EQH31_RS08635 (EQH31_09155) - 1702689..1703135 (-) 447 WP_000155399.1 GNAT family N-acetyltransferase -
  EQH31_RS08640 (EQH31_09160) cclA/cilC 1703205..1703864 (+) 660 WP_000565002.1 A24 family peptidase Machinery gene
  EQH31_RS08645 (EQH31_09165) - 1703916..1705067 (-) 1152 WP_000481756.1 XRE family transcriptional regulator -
  EQH31_RS08650 (EQH31_09170) - 1705082..1705813 (-) 732 WP_000934017.1 hypothetical protein -
  EQH31_RS08655 (EQH31_09175) - 1706033..1706143 (+) 111 Protein_1733 prepilin peptidase -
  EQH31_RS08660 (EQH31_09180) trpA 1706115..1706891 (-) 777 WP_001127048.1 tryptophan synthase subunit alpha -
  EQH31_RS08665 (EQH31_09185) trpB 1706884..1708107 (-) 1224 WP_000331287.1 tryptophan synthase subunit beta -
  EQH31_RS08670 (EQH31_09190) - 1708085..1708684 (-) 600 WP_000169887.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24806.89 Da        Isoelectric Point: 7.2761

>NTDB_id=337682 EQH31_RS08640 WP_000565002.1 1703205..1703864(+) (cclA/cilC) [Streptococcus pneumoniae strain TVO_1901938]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=337682 EQH31_RS08640 WP_000565002.1 1703205..1703864(+) (cclA/cilC) [Streptococcus pneumoniae strain TVO_1901938]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
ATACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATTGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTGTGATTATTTTTG
GTAAGCTACTACTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

97.717

100

0.977
  cclA/cilC Streptococcus pneumoniae Rx1

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae D39

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae R6

97.26

100

0.973
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

87.671

100

0.877

Multiple sequence alignment