Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   EQH33_RS00115 Genome accession   NZ_CP035247
Coordinates   23233..23469 (+) Length   78 a.a.
NCBI ID   WP_000939548.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901940     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 18233..28469
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH33_RS00105 (EQH33_00110) - 22001..22210 (+) 210 Protein_15 transposase -
  EQH33_RS00110 (EQH33_00115) - 22245..22967 (-) 723 Protein_16 transposase -
  EQH33_RS00115 (EQH33_00120) comW 23233..23469 (+) 237 WP_000939548.1 sigma(X)-activator ComW Regulator
  EQH33_RS00120 (EQH33_00125) - 23700..24986 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  EQH33_RS00125 (EQH33_00130) tadA 25187..25654 (+) 468 WP_000291870.1 tRNA adenosine(34) deaminase TadA -
  EQH33_RS00135 (EQH33_00140) - 25840..26283 (+) 444 WP_000701992.1 dUTP diphosphatase -
  EQH33_RS00140 (EQH33_00145) - 26285..26800 (+) 516 WP_001838385.1 histidine phosphatase family protein -
  EQH33_RS00145 (EQH33_00150) radA 26814..28175 (+) 1362 WP_074017595.1 DNA repair protein RadA Machinery gene

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9716.17 Da        Isoelectric Point: 6.7051

>NTDB_id=337490 EQH33_RS00115 WP_000939548.1 23233..23469(+) (comW) [Streptococcus pneumoniae strain TVO_1901940]
MLQKIYEQMTNFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=337490 EQH33_RS00115 WP_000939548.1 23233..23469(+) (comW) [Streptococcus pneumoniae strain TVO_1901940]
ATGTTACAAAAAATTTATGAGCAGATGACTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

97.436

100

0.974

  comW Streptococcus pneumoniae D39

97.436

100

0.974

  comW Streptococcus pneumoniae R6

97.436

100

0.974

  comW Streptococcus pneumoniae TIGR4

97.436

100

0.974

  comW Streptococcus mitis SK321

76.923

100

0.769

  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756


Multiple sequence alignment