Detailed information NTG0337202

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: EQH37_RS04715
• Genome accession: NZ_CP035243
• Coordinates: 930811..931764 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain TVO_1901946
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 925811..936764

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH37_RS04690 (EQH37_04975)	rpmG	926554..926703 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
EQH37_RS04695 (EQH37_04980)	secG	926743..926976 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
EQH37_RS04700 (EQH37_04985)	rnr	927078..929432 (+)	2355	WP_000654872.1	ribonuclease R	-
EQH37_RS04705 (EQH37_04990)	smpB	929395..929862 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
EQH37_RS04710 (EQH37_04995)	tehB	929878..930738 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
EQH37_RS04715 (EQH37_05000)	coiA	930811..931764 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
EQH37_RS04720 (EQH37_05005)	pepF	931783..933585 (+)	1803	WP_061367457.1	oligoendopeptidase F	Regulator
EQH37_RS04725 (EQH37_05010)	-	933587..934300 (+)	714	WP_077141330.1	O-methyltransferase	-
EQH37_RS04730 (EQH37_05015)	prsA	934367..935308 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
EQH37_RS04735 (EQH37_05020)	-	935425..935766 (-)	342	Protein_950	IS3 family transposase	-
EQH37_RS04740 (EQH37_05030)	-	936180..936275 (+)	96	Protein_951	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=337202 EQH37_RS04715 WP_000495909.1 930811..931764(+) (coiA) [Streptococcus pneumoniae strain TVO_1901946]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=337202 EQH37_RS04715 WP_000495909.1 930811..931764(+) (coiA) [Streptococcus pneumoniae strain TVO_1901946]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTGTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435