Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGG/cglG   Type   Machinery gene
Locus tag   EQH41_RS09785 Genome accession   NZ_CP035239
Coordinates   1943666..1944079 (-) Length   137 a.a.
NCBI ID   WP_000265622.1    Uniprot ID   Q8CY84
Organism   Streptococcus pneumoniae strain TVO_TIGR4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1938666..1949079
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH41_RS09760 (EQH41_10390) - 1939361..1940185 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  EQH41_RS09765 (EQH41_10395) rnpA 1940160..1940531 (-) 372 WP_000739253.1 ribonuclease P protein component -
  EQH41_RS10935 - 1940548..1940679 (-) 132 WP_000768904.1 hypothetical protein -
  EQH41_RS09770 (EQH41_10400) - 1940680..1941870 (-) 1191 WP_000167757.1 acetate kinase -
  EQH41_RS09775 (EQH41_10405) comYH 1941921..1942874 (-) 954 WP_000345135.1 class I SAM-dependent methyltransferase Machinery gene
  EQH41_RS09780 (EQH41_10410) - 1942935..1943529 (-) 595 Protein_1933 class I SAM-dependent methyltransferase -
  EQH41_RS09785 (EQH41_10415) comGG/cglG 1943666..1944079 (-) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH41_RS09790 (EQH41_10420) comGF/cglF 1944057..1944518 (-) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH41_RS09795 (EQH41_10425) comGE/cglE 1944481..1944783 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH41_RS09800 (EQH41_10430) comGD/cglD 1944746..1945150 (-) 405 WP_000588028.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH41_RS09805 (EQH41_10435) comGC/cglC 1945143..1945469 (-) 327 WP_000738627.1 comG operon protein ComGC Machinery gene
  EQH41_RS09810 (EQH41_10440) comGB/cglB 1945471..1946487 (-) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH41_RS09815 (EQH41_10445) comGA/cglA/cilD 1946435..1947376 (-) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH41_RS09820 (EQH41_10450) - 1947452..1947817 (-) 366 WP_000286415.1 DUF1033 family protein -
  EQH41_RS09825 (EQH41_10455) - 1947968..1949026 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence


Protein


Download         Length: 137 a.a.        Molecular weight: 16003.46 Da        Isoelectric Point: 10.2472

>NTDB_id=337002 EQH41_RS09785 WP_000265622.1 1943666..1944079(-) (comGG/cglG) [Streptococcus pneumoniae strain TVO_TIGR4]
MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNKEKLVAFAMAKRTKDKVEQESGEQFFNLGQVSYQNKK
TGLVTRVRTDKSQYEFLFPSVKIKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS

Nucleotide


Download         Length: 414 bp        

>NTDB_id=337002 EQH41_RS09785 WP_000265622.1 1943666..1944079(-) (comGG/cglG) [Streptococcus pneumoniae strain TVO_TIGR4]
GTGTGGAAAAAGAAAAAAGTTAAGGCAGGTGTTCTCCTCTACGCAGTCACCATAGCAGCCATCTTTAGTCTTTTGTTGCA
ATTTTATTTGAACCGACAAGTCGCCCACTATCAAGACTATGCTTTGAATAAAGAAAAATTGGTTGCTTTTGCTATGGCTA
AACGAACCAAAGATAAGGTTGAGCAAGAAAGTGGGGAACAGTTTTTTAATCTAGGTCAGGTAAGCTATCAAAACAAGAAA
ACTGGCTTAGTGACGAGGGTTCGTACGGATAAGAGCCAATATGAGTTTCTGTTTCCTTCAGTCAAAATCAAAGAAGAGAA
AAGAGATAAAAAGGAAGAGGTAGCGACCGATTCAAGCGAAAAAGTGGAGAAGAAAAAATCAGAAGAGAAGCCTGAAAAGA
AAGAGAATTCATAG

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q8CY84

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGG/cglG Streptococcus pneumoniae Rx1

100

100

1

  comGG/cglG Streptococcus pneumoniae D39

100

100

1

  comGG/cglG Streptococcus pneumoniae R6

100

100

1

  comGG/cglG Streptococcus pneumoniae TIGR4

100

100

1

  comGG/cglG Streptococcus mitis SK321

87.591

100

0.876

  comGG/cglG Streptococcus mitis NCTC 12261

89.256

88.321

0.788

  comYG Streptococcus mutans UA140

38.806

97.81

0.38

  comYG Streptococcus mutans UA159

38.806

97.81

0.38


Multiple sequence alignment