Detailed information NTG0336982

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: EQH41_RS08480
• Genome accession: NZ_CP035239
• Coordinates: 1714326..1714985 (+)
• Length: 219 a.a.
• NCBI ID: WP_000565004.1
• Uniprot ID: A0AA95DDC2
• Organism: Streptococcus pneumoniae strain TVO_TIGR4
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1709326..1719985

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH41_RS08440 (EQH41_09005)	mgaSpn	1709482..1710963 (-)	1482	WP_001205280.1	virulence factor transcriptional regulator MgaSpn	-
EQH41_RS08445 (EQH41_09010)	-	1711406..1711570 (+)	165	WP_001808603.1	GlsB/YeaQ/YmgE family stress response membrane protein	-
EQH41_RS08450 (EQH41_09015)	amaP	1711654..1712220 (+)	567	WP_000030213.1	alkaline shock response membrane anchor protein AmaP	-
EQH41_RS08455 (EQH41_09020)	-	1712232..1712402 (+)	171	WP_000455066.1	DUF2273 domain-containing protein	-
EQH41_RS08460 (EQH41_09025)	-	1712441..1713049 (+)	609	WP_000064115.1	Asp23/Gls24 family envelope stress response protein	-
EQH41_RS08465 (EQH41_09030)	-	1713080..1713283 (+)	204	WP_000109957.1	CsbD family protein	-
EQH41_RS08470 (EQH41_09035)	-	1713393..1713632 (-)	240	WP_001005784.1	transposase	-
EQH41_RS08475 (EQH41_09040)	-	1713810..1714256 (-)	447	WP_000155427.1	GNAT family N-acetyltransferase	-
EQH41_RS08480 (EQH41_09045)	cclA/cilC	1714326..1714985 (+)	660	WP_000565004.1	A24 family peptidase	Machinery gene
EQH41_RS08485 (EQH41_09050)	-	1715037..1716188 (-)	1152	WP_000481750.1	ImmA/IrrE family metallo-endopeptidase	-
EQH41_RS08490 (EQH41_09055)	-	1716203..1716934 (-)	732	WP_000934018.1	hypothetical protein	-
EQH41_RS08495 (EQH41_09060)	-	1717160..1717264 (+)	105	Protein_1709	prepilin peptidase	-
EQH41_RS08500 (EQH41_09065)	trpA	1717236..1718012 (-)	777	WP_001126999.1	tryptophan synthase subunit alpha	-
EQH41_RS08505 (EQH41_09070)	trpB	1718005..1719228 (-)	1224	WP_000331293.1	tryptophan synthase subunit beta	-
EQH41_RS08510 (EQH41_09075)	-	1719206..1719805 (-)	600	WP_000169894.1	phosphoribosylanthranilate isomerase	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24842.93 Da
• Isoelectric Point: 7.6165

>NTDB_id=336982 EQH41_RS08480 WP_000565004.1 1714326..1714985(+) (cclA/cilC) [Streptococcus pneumoniae strain TVO_TIGR4]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELSLG
LLFLLYSWGWLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFQLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=336982 EQH41_RS08480 WP_000565004.1 1714326..1714985(+) (cclA/cilC) [Streptococcus pneumoniae strain TVO_TIGR4]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTAGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAAGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGGATGGCTCTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCAGCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-88)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	100	100	1
cclA/cilC	Streptococcus pneumoniae Rx1	94.977	100	0.95
cclA/cilC	Streptococcus pneumoniae D39	94.977	100	0.95
cclA/cilC	Streptococcus pneumoniae R6	94.977	100	0.95
cclA/cilC	Streptococcus mitis SK321	91.781	100	0.918
cclA/cilC	Streptococcus mitis NCTC 12261	87.215	100	0.872