Detailed information NTG0336889

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: EQH42_RS04385
• Genome accession: NZ_CP035238
• Coordinates: 879651..880604 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495911.1
• Uniprot ID: Q8DQ27
• Organism: Streptococcus pneumoniae strain TVO_D39
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 874651..885604

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH42_RS04360 (EQH42_04630)	rpmG	875394..875543 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
EQH42_RS04365 (EQH42_04635)	secG	875583..875816 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
EQH42_RS04370 (EQH42_04640)	rnr	875918..878272 (+)	2355	WP_000654897.1	ribonuclease R	-
EQH42_RS04375 (EQH42_04645)	smpB	878235..878702 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
EQH42_RS04380 (EQH42_04650)	tehB	878718..879578 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
EQH42_RS04385 (EQH42_04655)	coiA	879651..880604 (+)	954	WP_000495911.1	competence protein CoiA	Machinery gene
EQH42_RS04390 (EQH42_04660)	pepF	880623..882425 (+)	1803	WP_000244122.1	oligoendopeptidase F	Regulator
EQH42_RS04395 (EQH42_04665)	-	882427..883140 (+)	714	WP_000230399.1	O-methyltransferase	-
EQH42_RS04400 (EQH42_04670)	prsA	883207..884148 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
EQH42_RS04405 (EQH42_04675)	-	884267..884608 (-)	342	Protein_882	transposase	-
EQH42_RS04410 (EQH42_04685)	-	885020..885115 (+)	96	Protein_883	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38143.79 Da
• Isoelectric Point: 9.1135

>NTDB_id=336889 EQH42_RS04385 WP_000495911.1 879651..880604(+) (coiA) [Streptococcus pneumoniae strain TVO_D39]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=336889 EQH42_RS04385 WP_000495911.1 879651..880604(+) (coiA) [Streptococcus pneumoniae strain TVO_D39]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCTTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGGAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGCCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: Q8DQ27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae Rx1	100	100	1
coiA	Streptococcus pneumoniae D39	100	100	1
coiA	Streptococcus pneumoniae R6	100	100	1
coiA	Streptococcus pneumoniae TIGR4	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435