Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   FXN59_RS02280 Genome accession   NZ_CP043004
Coordinates   429364..429975 (+) Length   203 a.a.
NCBI ID   WP_230583193.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain HK_973     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 424364..434975
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FXN59_RS02240 (FXN59_02240) mutM 424367..425182 (-) 816 WP_148323805.1 bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase -
  FXN59_RS02245 (FXN59_02245) rpmG 425265..425435 (-) 171 WP_005544948.1 50S ribosomal protein L33 -
  FXN59_RS02250 (FXN59_02250) rpmB 425447..425683 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  FXN59_RS02255 (FXN59_02255) radC 425892..426551 (-) 660 WP_005562038.1 DNA repair protein RadC Machinery gene
  FXN59_RS02260 (FXN59_02260) coaBC 426729..427928 (+) 1200 WP_005562040.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  FXN59_RS02265 (FXN59_02265) dut 427997..428452 (+) 456 WP_005562041.1 dUTP diphosphatase -
  FXN59_RS02270 (FXN59_02270) slmA 428452..429051 (+) 600 WP_005540234.1 nucleoid occlusion factor SlmA -
  FXN59_RS02275 (FXN59_02275) - 429075..429293 (+) 219 WP_005540236.1 YheU family protein -
  FXN59_RS02280 (FXN59_02280) crp 429364..429975 (+) 612 WP_230583193.1 cAMP-activated global transcriptional regulator CRP Regulator
  FXN59_RS02285 (FXN59_02285) gorA 430108..431478 (-) 1371 WP_151294155.1 glutathione-disulfide reductase -
  FXN59_RS02290 (FXN59_02290) - 431573..432418 (-) 846 WP_053330008.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -

Sequence

Protein


Download         Length: 203 a.a.        Molecular weight: 23014.59 Da        Isoelectric Point: 7.8328

>NTDB_id=334135 FXN59_RS02280 WP_230583193.1 429364..429975(+) (crp) [Aggregatibacter actinomycetemcomitans strain HK_973]
MDPTLEWFLSHCHIHKYPSKSTLINAGEKAETLYYLIQGSVSVLVKDEDGKEMILTYLSQGDFFGEAGLFEEGQRRSAWI
KAKSSCEVAEISYRKFRQLIQVNPEILMYLTAQLAYRLQNTSRQVSNLAFLDVTGRIAQTLLNLAKMPEAMTHPDGMQIK
ITRQEIGQMVGCSRETVGRILKMLEDQHLISAHGKTIVVYGTR

Nucleotide


Download         Length: 612 bp        

>NTDB_id=334135 FXN59_RS02280 WP_230583193.1 429364..429975(+) (crp) [Aggregatibacter actinomycetemcomitans strain HK_973]
ATGGATCCGACACTTGAGTGGTTTTTATCCCACTGCCATATCCATAAATATCCGTCTAAAAGCACATTAATCAACGCCGG
CGAAAAAGCCGAGACACTTTATTATTTAATTCAAGGCTCCGTGTCCGTTTTGGTCAAAGACGAAGACGGCAAAGAAATGA
TCCTCACCTATTTAAGCCAAGGGGATTTTTTCGGCGAAGCGGGCTTATTTGAAGAAGGACAACGTCGTTCTGCGTGGATT
AAAGCAAAATCCTCCTGTGAAGTGGCGGAAATTTCTTATCGTAAATTTCGCCAGCTGATTCAAGTCAACCCTGAGATTCT
GATGTATCTTACGGCCCAATTAGCGTATCGGTTACAAAACACTTCGCGCCAAGTAAGTAATTTAGCCTTTTTAGATGTCA
CCGGTCGCATTGCGCAAACCTTGCTCAATCTGGCAAAAATGCCGGAAGCGATGACTCACCCGGACGGTATGCAAATTAAA
ATCACCCGCCAGGAAATCGGACAAATGGTCGGTTGTTCGCGGGAAACCGTCGGGCGTATTCTGAAAATGCTGGAAGATCA
ACACCTCATCTCGGCACACGGCAAAACCATCGTAGTTTACGGCACCCGCTAA

Domains

Predicted by InterProScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(135-199)

Cyclic nucleotide-binding domain (cNMP_binding)

(16-102)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

82.178

99.507

0.818
  crp Haemophilus influenzae Rd KW20

80.693

99.507

0.803
  crp Acinetobacter baumannii D1279779

47.236

98.03

0.463