Detailed information NTG0334024

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: FWK45_RS00770
• Genome accession: NZ_CP043001
• Coordinates: 140425..141069 (-)
• Length: 214 a.a.
• NCBI ID: WP_011608291.1
• Uniprot ID: -
• Organism: Histophilus somni strain UOC-KLM-ATR-04
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 135425..146069

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FWK45_RS00740 (FWK45_00740)	yidD	135743..136003 (-)	261	WP_011608286.1	membrane protein insertion efficiency factor YidD	-
FWK45_RS00745 (FWK45_00745)	rnpA	135967..136326 (-)	360	WP_011608287.1	ribonuclease P protein component	-
FWK45_RS00750 (FWK45_00750)	rpmH	136341..136475 (-)	135	WP_007241546.1	50S ribosomal protein L34	-
FWK45_RS00755 (FWK45_00755)	dnaA	136818..138176 (+)	1359	WP_011608288.1	chromosomal replication initiator protein DnaA	-
FWK45_RS00760 (FWK45_00760)	dnaN	138188..139288 (+)	1101	WP_132994584.1	DNA polymerase III subunit beta	-
FWK45_RS00765 (FWK45_00765)	recF	139292..140368 (+)	1077	WP_132994585.1	DNA replication/repair protein RecF	-
FWK45_RS00770 (FWK45_00770)	crp	140425..141069 (-)	645	WP_011608291.1	cAMP-activated global transcriptional regulator CRP	Regulator
FWK45_RS00775 (FWK45_00775)	-	141082..141306 (-)	225	WP_012341336.1	YheU family protein	-
FWK45_RS00780 (FWK45_00780)	slmA	141341..142000 (-)	660	WP_011608293.1	nucleoid occlusion factor SlmA	-
FWK45_RS00785 (FWK45_00785)	dut	142000..142455 (-)	456	WP_011608294.1	dUTP diphosphatase	-
FWK45_RS00790 (FWK45_00790)	coaBC	142452..143678 (-)	1227	WP_132994586.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
FWK45_RS00795 (FWK45_00795)	radC	143851..144519 (+)	669	WP_011608296.1	DNA repair protein RadC	Machinery gene
FWK45_RS00800 (FWK45_00800)	rpmB	144740..144976 (+)	237	WP_011608297.1	50S ribosomal protein L28	-
FWK45_RS00805 (FWK45_00805)	rpmG	144988..145158 (+)	171	WP_005542835.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 214 a.a.
• Molecular weight: 24029.75 Da
• Isoelectric Point: 7.4775

>NTDB_id=334024 FWK45_RS00770 WP_011608291.1 140425..141069(-) (crp) [Histophilus somni strain UOC-KLM-ATR-04]
MLEQQGQSAPSMDPTLEWFLSHCHIHKYSAKSSLIHAGEKAETLYYLIRGSVAVMVKDEEGKEMILTYLSQGDFFGEAGL
FDETQPRSAWVKAKSSCEIAEISYKKFRQLIQVNPEILMYLAGQLAHRLQNTSKQVSNLAFLDVTGRIAQTLLNLAKMPD
AMTHPDGMQIKITRQEIGQMVGCSRETVGRILKMLEDQHLISAHGKTIVVYGTR

Nucleotide

• Length: 645 bp

>NTDB_id=334024 FWK45_RS00770 WP_011608291.1 140425..141069(-) (crp) [Histophilus somni strain UOC-KLM-ATR-04]
ATGTTAGAACAACAAGGACAATCAGCACCATCGATGGATCCGACGTTAGAGTGGTTCCTATCTCATTGTCACATTCATAA
ATACTCAGCAAAAAGCTCCCTCATTCATGCTGGAGAAAAAGCGGAAACCCTTTATTATTTAATTAGAGGGTCTGTTGCCG
TGATGGTAAAAGATGAGGAAGGTAAAGAAATGATTTTGACTTATTTAAGTCAAGGTGATTTTTTTGGCGAAGCTGGTTTA
TTTGATGAAACACAGCCTCGTTCGGCTTGGGTTAAAGCTAAAAGCTCATGTGAAATTGCAGAAATTTCTTATAAAAAATT
TCGCCAATTAATTCAAGTTAATCCAGAAATTTTAATGTATTTAGCCGGTCAATTAGCTCATCGTTTACAAAATACTTCAA
AGCAGGTAAGCAATCTGGCATTTTTAGATGTGACAGGTCGTATCGCTCAAACCTTGTTAAATTTAGCTAAGATGCCTGAT
GCAATGACTCATCCGGACGGTATGCAAATTAAAATTACTCGTCAGGAAATAGGACAAATGGTAGGTTGCTCACGAGAAAC
TGTTGGGCGTATTTTGAAAATGTTAGAAGATCAGCATTTGATTTCAGCACATGGCAAAACTATTGTTGTGTATGGTACAA
GATAA

Domains

Predicted by InterProScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (146-210)

• Cyclic nucleotide-binding domain (cNMP_binding) (27-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	81.463	95.794	0.78
crp	Haemophilus influenzae Rd KW20	78.846	97.196	0.766
crp	Acinetobacter baumannii D1279779	44.221	92.991	0.411