Detailed information NTG0033400

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: SPT_RS09015
• Genome accession: NC_012469
• Coordinates: 1717081..1718148 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159553.1
• Uniprot ID: A0A0T8CF10
• Organism: Streptococcus pneumoniae Taiwan19F-14
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1712081..1723148

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPT_RS08980 (SPT_1803)	treR	1712168..1712878 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
SPT_RS12610	-	1713035..1714178 (+)	1144	Protein_1725	transposase	-
SPT_RS09000	-	1714345..1715691 (+)	1347	WP_041179004.1	IS1380-like element ISSpn5 family transposase	-
SPT_RS09005	-	1715884..1716069 (+)	186	Protein_1727	transposase	-
SPT_RS09010 (SPT_1809)	amiF	1716144..1717070 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
SPT_RS09015 (SPT_1810)	amiE	1717081..1718148 (-)	1068	WP_000159553.1	ABC transporter ATP-binding protein	Regulator
SPT_RS09020 (SPT_1811)	amiD	1718157..1719083 (-)	927	WP_000103702.1	oligopeptide ABC transporter permease OppC	Regulator
SPT_RS09025 (SPT_1812)	amiC	1719083..1720579 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
SPT_RS09030 (SPT_1813)	amiA3	1720646..1722625 (-)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39437.04 Da
• Isoelectric Point: 4.8002

>NTDB_id=33400 SPT_RS09015 WP_000159553.1 1717081..1718148(-) (amiE) [Streptococcus pneumoniae Taiwan19F-14]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=33400 SPT_RS09015 WP_000159553.1 1717081..1718148(-) (amiE) [Streptococcus pneumoniae Taiwan19F-14]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTTGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0T8CF10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.761	100	0.868
amiE	Streptococcus thermophilus LMD-9	86.761	100	0.868
oppD	Streptococcus mutans UA159	54.545	99.155	0.541