Detailed information NTG0033398

Bioinformatically predicted

Overview

• Name: treR
• Type: Regulator
• Locus tag: SPT_RS08980
• Genome accession: NC_012469
• Coordinates: 1712168..1712878 (+)
• Length: 236 a.a.
• NCBI ID: WP_000760673.1
• Uniprot ID: A0A062WVH4
• Organism: Streptococcus pneumoniae Taiwan19F-14
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1713035..1716069	1712168..1712878	flank	157

Gene organization within MGE regions

Location: 1712168..1716069

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPT_RS08980 (SPT_1803)	treR	1712168..1712878 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
SPT_RS12610	-	1713035..1714178 (+)	1144	Protein_1725	transposase	-
SPT_RS09000	-	1714345..1715691 (+)	1347	WP_041179004.1	IS1380-like element ISSpn5 family transposase	-
SPT_RS09005	-	1715884..1716069 (+)	186	Protein_1727	transposase	-

Sequence

Protein

• Length: 236 a.a.
• Molecular weight: 27607.78 Da
• Isoelectric Point: 8.9698

>NTDB_id=33398 SPT_RS08980 WP_000760673.1 1712168..1712878(+) (treR) [Streptococcus pneumoniae Taiwan19F-14]
MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVRKALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLT
SYQELVKELGLRSKTNVVSLDKIIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTESRHKLEKFRFVDFAKRKK

Nucleotide

• Length: 711 bp

>NTDB_id=33398 SPT_RS08980 WP_000760673.1 1712168..1712878(+) (treR) [Streptococcus pneumoniae Taiwan19F-14]
ATGAAGAAATACCAACAATTATTTAAGCAAATCCAAGAAACCATTCAAAACGAGACTTACGCTGTCGGAGATTTCCTTCC
TAGCGAGCACGACCTTATGGAGCAATATCAAGTGAGTCGTGATACCGTCCGAAAGGCCCTGTCTCTCCTCCAAGAGGAAG
GATTGATCAAAAAGATAAGAGGGCAAGGTTCTCAAGTCGTCAAAGAAGAAACCGTCAATTTCCCTGTATCCAACCTAACC
AGCTACCAAGAACTAGTTAAAGAACTTGGACTGCGCTCTAAAACCAACGTGGTCAGTCTGGACAAGATTATTATTGATAA
AAAATCCTCACTGATAACCGGTTTCCCAGAGTTTCGGATGGTTTGGAAGGTGGTCCGCCAGCGTGTGGTGGATGATCTGG
TATCCGTTCTGGATACAGACTATCTGGATATGGAACTCATCCCAAATCTCACTCGCCAAATTGCTGAGCAGTCTATCTAT
TCTTATATAGAAAATGGCCTCAAACTCCTTATTGATTATGCTCAGAAGGAAATCACCATTGACCACTCAAGCGACCGAGA
CAAGATTCTCATGGACATTGGCAAAGACCCTTATGTCGTTTCGATTAAATCAAAAGTCTATCTCCAAGACGGACGCCAAT
TTCAGTTTACCGAAAGTCGCCATAAGTTAGAGAAATTTAGATTTGTAGATTTTGCAAAACGCAAGAAATAA

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, gntR family (GntR) (3-66)

• UTRA domain (UTRA) (89-227)

3D structure

• AlphaFold DB: A0A062WVH4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
treR	Streptococcus mutans UA159	59.322	100	0.593