Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FRD49_RS03855 Genome accession   NZ_CP042994
Coordinates   793299..793973 (+) Length   224 a.a.
NCBI ID   WP_002051287.1    Uniprot ID   A0AA36K948
Organism   Acinetobacter nosocomialis strain J1A     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 788299..798973
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FRD49_RS03840 (FRD49_03840) - 788354..789601 (+) 1248 WP_032010131.1 MFS transporter -
  FRD49_RS03845 (FRD49_03845) - 790143..791447 (+) 1305 WP_004712196.1 DcaP family trimeric outer membrane transporter -
  FRD49_RS03850 (FRD49_03850) - 791635..793284 (+) 1650 WP_032010132.1 phosphoethanolamine transferase -
  FRD49_RS03855 (FRD49_03855) ciaR 793299..793973 (+) 675 WP_002051287.1 DNA-binding response regulator PmrA Regulator
  FRD49_RS03860 (FRD49_03860) - 793999..795333 (+) 1335 WP_004712203.1 two-component system sensor histidine kinase PmrB -
  FRD49_RS03865 (FRD49_03865) - 795330..796028 (-) 699 WP_004885453.1 phosphatase PAP2 family protein -
  FRD49_RS03870 (FRD49_03870) - 796288..797475 (-) 1188 WP_004885455.1 ammonium transporter -
  FRD49_RS03880 (FRD49_03880) - 797781..798665 (-) 885 WP_032010134.1 LysR family transcriptional regulator -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25535.39 Da        Isoelectric Point: 5.3246

>NTDB_id=333967 FRD49_RS03855 WP_002051287.1 793299..793973(+) (ciaR) [Acinetobacter nosocomialis strain J1A]
MTKILMIEDDFMIAESTTTLLQYHQFEVEWVNNGLDGLAQLAKNKFDLILLDLGLPMMDGMQVLKQIRQRAATPVLIISA
RDQLQNRVDGLNLGADDYLIKPYEFDELLARIHALLRRSGVEAQLASQDQLLESGDLVLNVEQHIATFKGQRIDLSNREW
AILIPLMSHPNKIFSKANLEDKLYDFDSDVTSNTIEVYVHHLRAKLGKDFIRTIRGLGYRLGQS

Nucleotide


Download         Length: 675 bp        

>NTDB_id=333967 FRD49_RS03855 WP_002051287.1 793299..793973(+) (ciaR) [Acinetobacter nosocomialis strain J1A]
ATGACAAAAATCTTGATGATTGAAGATGATTTTATGATTGCAGAATCAACAACGACGTTGCTGCAATATCATCAATTTGA
GGTGGAATGGGTCAATAACGGTTTAGATGGTTTGGCCCAATTAGCAAAGAATAAGTTTGATCTCATTCTTTTAGACTTGG
GATTGCCAATGATGGATGGTATGCAAGTTTTAAAGCAGATTCGTCAAAGAGCAGCAACACCAGTCTTGATTATCTCTGCA
CGTGACCAACTGCAAAACCGTGTTGATGGTCTGAATTTGGGAGCAGATGATTACTTAATTAAGCCTTATGAGTTTGATGA
ATTACTCGCTCGTATTCATGCTTTATTACGCCGTAGTGGCGTAGAGGCTCAACTTGCAAGCCAAGATCAACTACTAGAAA
GCGGTGATCTGGTTTTAAATGTTGAACAGCACATTGCAACATTTAAAGGGCAACGTATTGATTTATCGAATCGTGAATGG
GCAATCTTGATTCCGCTTATGAGTCATCCAAATAAAATTTTCTCAAAAGCTAATTTGGAAGATAAGTTATATGACTTTGA
TAGTGATGTGACCAGCAACACGATTGAGGTATATGTCCATCATTTAAGGGCTAAGTTGGGTAAAGACTTTATTCGAACTA
TCCGAGGACTGGGTTACCGTTTAGGGCAATCATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AA36K948

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.496

100

0.388
  ciaR Streptococcus pneumoniae D39

38.496

100

0.388
  ciaR Streptococcus pneumoniae R6

38.496

100

0.388
  ciaR Streptococcus pneumoniae TIGR4

38.496

100

0.388
  ciaR Streptococcus mutans UA159

37.445

100

0.379
  micA Streptococcus pneumoniae Cp1015

36.404

100

0.371