Detailed information NTG0333883

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: FWK61_RS09050
• Genome accession: NZ_CP042992
• Coordinates: 1971841..1972485 (+)
• Length: 214 a.a.
• NCBI ID: WP_011608291.1
• Uniprot ID: -
• Organism: Histophilus somni strain UOC-KLM-ATR-013
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1966841..1977485

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FWK61_RS09015 (FWK61_09015)	rpmG	1967752..1967922 (-)	171	WP_005542835.1	50S ribosomal protein L33	-
FWK61_RS09020 (FWK61_09020)	rpmB	1967934..1968170 (-)	237	WP_011608297.1	50S ribosomal protein L28	-
FWK61_RS09025 (FWK61_09025)	radC	1968391..1969059 (-)	669	WP_011608296.1	DNA repair protein RadC	Machinery gene
FWK61_RS09030 (FWK61_09030)	coaBC	1969232..1970458 (+)	1227	WP_132994586.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
FWK61_RS09035 (FWK61_09035)	dut	1970455..1970910 (+)	456	WP_011608294.1	dUTP diphosphatase	-
FWK61_RS09040 (FWK61_09040)	slmA	1970910..1971569 (+)	660	WP_011608293.1	nucleoid occlusion factor SlmA	-
FWK61_RS09045 (FWK61_09045)	-	1971604..1971828 (+)	225	WP_012341336.1	YheU family protein	-
FWK61_RS09050 (FWK61_09050)	crp	1971841..1972485 (+)	645	WP_011608291.1	cAMP-activated global transcriptional regulator CRP	Regulator
FWK61_RS09055 (FWK61_09055)	recF	1972542..1973618 (-)	1077	WP_132994585.1	DNA replication/repair protein RecF	-
FWK61_RS09060 (FWK61_09060)	dnaN	1973622..1974722 (-)	1101	WP_132994584.1	DNA polymerase III subunit beta	-
FWK61_RS09065 (FWK61_09065)	dnaA	1974734..1976092 (-)	1359	WP_011608288.1	chromosomal replication initiator protein DnaA	-
FWK61_RS09070 (FWK61_09070)	rpmH	1976435..1976569 (+)	135	WP_007241546.1	50S ribosomal protein L34	-
FWK61_RS09075 (FWK61_09075)	rnpA	1976584..1976943 (+)	360	WP_011608287.1	ribonuclease P protein component	-
FWK61_RS09080 (FWK61_09080)	yidD	1976907..1977167 (+)	261	WP_011608286.1	membrane protein insertion efficiency factor YidD	-

Sequence

Protein

• Length: 214 a.a.
• Molecular weight: 24029.75 Da
• Isoelectric Point: 7.4775

>NTDB_id=333883 FWK61_RS09050 WP_011608291.1 1971841..1972485(+) (crp) [Histophilus somni strain UOC-KLM-ATR-013]
MLEQQGQSAPSMDPTLEWFLSHCHIHKYSAKSSLIHAGEKAETLYYLIRGSVAVMVKDEEGKEMILTYLSQGDFFGEAGL
FDETQPRSAWVKAKSSCEIAEISYKKFRQLIQVNPEILMYLAGQLAHRLQNTSKQVSNLAFLDVTGRIAQTLLNLAKMPD
AMTHPDGMQIKITRQEIGQMVGCSRETVGRILKMLEDQHLISAHGKTIVVYGTR

Nucleotide

• Length: 645 bp

>NTDB_id=333883 FWK61_RS09050 WP_011608291.1 1971841..1972485(+) (crp) [Histophilus somni strain UOC-KLM-ATR-013]
ATGTTAGAACAACAAGGACAATCAGCACCATCGATGGATCCGACGTTAGAGTGGTTCCTATCTCATTGTCACATTCATAA
ATACTCAGCAAAAAGCTCCCTCATTCATGCTGGAGAAAAAGCGGAAACCCTTTATTATTTAATTAGAGGGTCTGTTGCCG
TGATGGTAAAAGATGAGGAAGGTAAAGAAATGATTTTGACTTATTTAAGTCAAGGTGATTTTTTTGGCGAAGCTGGTTTA
TTTGATGAAACACAGCCTCGTTCGGCTTGGGTTAAAGCTAAAAGCTCATGTGAAATTGCAGAAATTTCTTATAAAAAATT
TCGCCAATTAATTCAAGTTAATCCAGAAATTTTAATGTATTTAGCCGGTCAATTAGCTCATCGTTTACAAAATACTTCAA
AGCAGGTAAGCAATCTGGCATTTTTAGATGTGACAGGTCGTATCGCTCAAACCTTGTTAAATTTAGCTAAGATGCCTGAT
GCAATGACTCATCCGGACGGTATGCAAATTAAAATTACTCGTCAGGAAATAGGACAAATGGTAGGTTGCTCACGAGAAAC
TGTTGGGCGTATTTTGAAAATGTTAGAAGATCAGCATTTGATTTCAGCACATGGCAAAACTATTGTTGTGTATGGTACAA
GATAA

Domains

Predicted by InterProScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (146-210)

• Cyclic nucleotide-binding domain (cNMP_binding) (27-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	81.463	95.794	0.78
crp	Haemophilus influenzae Rd KW20	78.846	97.196	0.766
crp	Acinetobacter baumannii D1279779	44.221	92.991	0.411