Detailed information NTG0033381

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: SPT_RS06075
• Genome accession: NC_012469
• Coordinates: 1168781..1169734 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae Taiwan19F-14
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1163781..1174734

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPT_RS12550	-	1164262..1164357 (-)	96	Protein_1165	IS630 family transposase	-
SPT_RS06055 (SPT_1221)	-	1164770..1165111 (+)	342	Protein_1166	transposase	-
SPT_RS06060 (SPT_1222)	prsA	1165228..1166169 (-)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
SPT_RS06065 (SPT_1223)	-	1166236..1166949 (-)	714	WP_000230400.1	O-methyltransferase	-
SPT_RS06070 (SPT_1224)	pepF	1166951..1168762 (-)	1812	WP_000244158.1	oligoendopeptidase F	Regulator
SPT_RS06075 (SPT_1225)	coiA	1168781..1169734 (-)	954	WP_000495909.1	competence protein CoiA	Machinery gene
SPT_RS06080 (SPT_1226)	tehB	1169807..1170667 (-)	861	WP_000413757.1	SAM-dependent methyltransferase TehB	-
SPT_RS06085 (SPT_1227)	smpB	1170683..1171150 (-)	468	WP_001051750.1	SsrA-binding protein SmpB	-
SPT_RS06090 (SPT_1228)	rnr	1171113..1173467 (-)	2355	WP_000654886.1	ribonuclease R	-
SPT_RS06095 (SPT_1229)	secG	1173569..1173802 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
SPT_RS06100 (SPT_1230)	rpmG	1173842..1173991 (-)	150	WP_001810029.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=33381 SPT_RS06075 WP_000495909.1 1168781..1169734(-) (coiA) [Streptococcus pneumoniae Taiwan19F-14]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=33381 SPT_RS06075 WP_000495909.1 1168781..1169734(-) (coiA) [Streptococcus pneumoniae Taiwan19F-14]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTAAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435