Detailed information NTG0333773

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: FWK55_RS08910
• Genome accession: NZ_CP042990
• Coordinates: 1971809..1972453 (+)
• Length: 214 a.a.
• NCBI ID: WP_011608291.1
• Uniprot ID: -
• Organism: Histophilus somni strain UOC-KLM-ATR-011
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1966809..1977453

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FWK55_RS08875 (FWK55_08875)	rpmG	1967720..1967890 (-)	171	WP_005542835.1	50S ribosomal protein L33	-
FWK55_RS08880 (FWK55_08880)	rpmB	1967902..1968138 (-)	237	WP_011608297.1	50S ribosomal protein L28	-
FWK55_RS08885 (FWK55_08885)	radC	1968359..1969027 (-)	669	WP_011608296.1	DNA repair protein RadC	Machinery gene
FWK55_RS08890 (FWK55_08890)	coaBC	1969200..1970426 (+)	1227	WP_075293534.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
FWK55_RS08895 (FWK55_08895)	dut	1970423..1970878 (+)	456	WP_011608294.1	dUTP diphosphatase	-
FWK55_RS08900 (FWK55_08900)	slmA	1970878..1971537 (+)	660	WP_011608293.1	nucleoid occlusion factor SlmA	-
FWK55_RS08905 (FWK55_08905)	-	1971572..1971796 (+)	225	WP_012341336.1	YheU family protein	-
FWK55_RS08910 (FWK55_08910)	crp	1971809..1972453 (+)	645	WP_011608291.1	cAMP-activated global transcriptional regulator CRP	Regulator
FWK55_RS08915 (FWK55_08915)	recF	1972510..1973586 (-)	1077	WP_075293535.1	DNA replication/repair protein RecF	-
FWK55_RS08920 (FWK55_08920)	dnaN	1973590..1974690 (-)	1101	WP_075293536.1	DNA polymerase III subunit beta	-
FWK55_RS08925 (FWK55_08925)	dnaA	1974702..1976060 (-)	1359	WP_011608288.1	chromosomal replication initiator protein DnaA	-
FWK55_RS08930 (FWK55_08930)	rpmH	1976403..1976537 (+)	135	WP_007241546.1	50S ribosomal protein L34	-
FWK55_RS08935 (FWK55_08935)	rnpA	1976552..1976911 (+)	360	WP_011608287.1	ribonuclease P protein component	-
FWK55_RS08940 (FWK55_08940)	yidD	1976875..1977135 (+)	261	WP_011608286.1	membrane protein insertion efficiency factor YidD	-

Sequence

Protein

• Length: 214 a.a.
• Molecular weight: 24029.75 Da
• Isoelectric Point: 7.4775

>NTDB_id=333773 FWK55_RS08910 WP_011608291.1 1971809..1972453(+) (crp) [Histophilus somni strain UOC-KLM-ATR-011]
MLEQQGQSAPSMDPTLEWFLSHCHIHKYSAKSSLIHAGEKAETLYYLIRGSVAVMVKDEEGKEMILTYLSQGDFFGEAGL
FDETQPRSAWVKAKSSCEIAEISYKKFRQLIQVNPEILMYLAGQLAHRLQNTSKQVSNLAFLDVTGRIAQTLLNLAKMPD
AMTHPDGMQIKITRQEIGQMVGCSRETVGRILKMLEDQHLISAHGKTIVVYGTR

Nucleotide

• Length: 645 bp

>NTDB_id=333773 FWK55_RS08910 WP_011608291.1 1971809..1972453(+) (crp) [Histophilus somni strain UOC-KLM-ATR-011]
ATGTTAGAACAACAAGGACAATCAGCACCATCGATGGATCCGACGTTAGAGTGGTTCCTATCTCATTGTCACATTCATAA
ATACTCAGCAAAAAGCTCCCTCATTCATGCTGGAGAAAAGGCGGAAACCCTTTATTATTTAATTAGAGGGTCTGTTGCCG
TGATGGTAAAAGATGAGGAAGGTAAAGAAATGATTTTGACTTATTTAAGTCAAGGTGATTTTTTTGGCGAAGCTGGTTTA
TTTGATGAAACACAGCCTCGTTCGGCTTGGGTTAAAGCTAAAAGCTCATGTGAAATTGCAGAAATTTCTTATAAAAAATT
TCGCCAATTAATTCAAGTTAATCCAGAAATTTTAATGTATTTAGCCGGTCAATTAGCTCATCGTTTACAAAATACTTCAA
AGCAGGTAAGCAATTTGGCATTTTTAGATGTGACAGGTCGTATCGCTCAAACCTTGTTAAATTTAGCTAAGATGCCTGAT
GCAATGACTCATCCGGACGGTATGCAAATTAAAATTACTCGTCAGGAAATAGGACAAATGGTAGGTTGCTCACGAGAAAC
TGTTGGGCGTATTTTGAAAATGTTAGAAGATCAGCATTTAATTTCAGCACATGGCAAAACTATTGTTGTGTATGGTACAA
GATAA

Domains

Predicted by InterProScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (146-210)

• Cyclic nucleotide-binding domain (cNMP_binding) (27-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	81.463	95.794	0.78
crp	Haemophilus influenzae Rd KW20	78.846	97.196	0.766
crp	Acinetobacter baumannii D1279779	44.221	92.991	0.411