Detailed information NTG0333382

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: FWK43_RS09045
• Genome accession: NZ_CP042983
• Coordinates: 1971832..1972476 (+)
• Length: 214 a.a.
• NCBI ID: WP_011608291.1
• Uniprot ID: -
• Organism: Histophilus somni strain UOC-KLM-ATR-01
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1966832..1977476

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FWK43_RS09010 (FWK43_09010)	rpmG	1967743..1967913 (-)	171	WP_005542835.1	50S ribosomal protein L33	-
FWK43_RS09015 (FWK43_09015)	rpmB	1967925..1968161 (-)	237	WP_011608297.1	50S ribosomal protein L28	-
FWK43_RS09020 (FWK43_09020)	radC	1968382..1969050 (-)	669	WP_011608296.1	DNA repair protein RadC	Machinery gene
FWK43_RS09025 (FWK43_09025)	coaBC	1969223..1970449 (+)	1227	WP_132994586.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
FWK43_RS09030 (FWK43_09030)	dut	1970446..1970901 (+)	456	WP_011608294.1	dUTP diphosphatase	-
FWK43_RS09035 (FWK43_09035)	slmA	1970901..1971560 (+)	660	WP_011608293.1	nucleoid occlusion factor SlmA	-
FWK43_RS09040 (FWK43_09040)	-	1971595..1971819 (+)	225	WP_012341336.1	YheU family protein	-
FWK43_RS09045 (FWK43_09045)	crp	1971832..1972476 (+)	645	WP_011608291.1	cAMP-activated global transcriptional regulator CRP	Regulator
FWK43_RS09050 (FWK43_09050)	recF	1972533..1973609 (-)	1077	WP_132994585.1	DNA replication/repair protein RecF	-
FWK43_RS09055 (FWK43_09055)	dnaN	1973613..1974713 (-)	1101	WP_132994584.1	DNA polymerase III subunit beta	-
FWK43_RS09060 (FWK43_09060)	dnaA	1974725..1976083 (-)	1359	WP_011608288.1	chromosomal replication initiator protein DnaA	-
FWK43_RS09065 (FWK43_09065)	rpmH	1976426..1976560 (+)	135	WP_007241546.1	50S ribosomal protein L34	-
FWK43_RS09070 (FWK43_09070)	rnpA	1976575..1976934 (+)	360	WP_011608287.1	ribonuclease P protein component	-
FWK43_RS09075 (FWK43_09075)	yidD	1976898..1977158 (+)	261	WP_011608286.1	membrane protein insertion efficiency factor YidD	-

Sequence

Protein

• Length: 214 a.a.
• Molecular weight: 24029.75 Da
• Isoelectric Point: 7.4775

>NTDB_id=333382 FWK43_RS09045 WP_011608291.1 1971832..1972476(+) (crp) [Histophilus somni strain UOC-KLM-ATR-01]
MLEQQGQSAPSMDPTLEWFLSHCHIHKYSAKSSLIHAGEKAETLYYLIRGSVAVMVKDEEGKEMILTYLSQGDFFGEAGL
FDETQPRSAWVKAKSSCEIAEISYKKFRQLIQVNPEILMYLAGQLAHRLQNTSKQVSNLAFLDVTGRIAQTLLNLAKMPD
AMTHPDGMQIKITRQEIGQMVGCSRETVGRILKMLEDQHLISAHGKTIVVYGTR

Nucleotide

• Length: 645 bp

>NTDB_id=333382 FWK43_RS09045 WP_011608291.1 1971832..1972476(+) (crp) [Histophilus somni strain UOC-KLM-ATR-01]
ATGTTAGAACAACAAGGACAATCAGCACCATCGATGGATCCGACGTTAGAGTGGTTCCTATCTCATTGTCACATTCATAA
ATACTCAGCAAAAAGCTCCCTCATTCATGCTGGAGAAAAAGCGGAAACCCTTTATTATTTAATTAGAGGGTCTGTTGCCG
TGATGGTAAAAGATGAGGAAGGTAAAGAAATGATTTTGACTTATTTAAGTCAAGGTGATTTTTTTGGCGAAGCTGGTTTA
TTTGATGAAACACAGCCTCGTTCGGCTTGGGTTAAAGCTAAAAGCTCATGTGAAATTGCAGAAATTTCTTATAAAAAATT
TCGCCAATTAATTCAAGTTAATCCAGAAATTTTAATGTATTTAGCCGGTCAATTAGCTCATCGTTTACAAAATACTTCAA
AGCAGGTAAGCAATCTGGCATTTTTAGATGTGACAGGTCGTATCGCTCAAACCTTGTTAAATTTAGCTAAGATGCCTGAT
GCAATGACTCATCCGGACGGTATGCAAATTAAAATTACTCGTCAGGAAATAGGACAAATGGTAGGTTGCTCACGAGAAAC
TGTTGGGCGTATTTTGAAAATGTTAGAAGATCAGCATTTGATTTCAGCACATGGCAAAACTATTGTTGTGTATGGTACAA
GATAA

Domains

Predicted by InterProScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (146-210)

• Cyclic nucleotide-binding domain (cNMP_binding) (27-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	81.463	95.794	0.78
crp	Haemophilus influenzae Rd KW20	78.846	97.196	0.766
crp	Acinetobacter baumannii D1279779	44.221	92.991	0.411