Detailed information NTG0033202

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: HIBPF_RS06425
• Genome accession: NC_014920
• Coordinates: 1271245..1271919 (-)
• Length: 224 a.a.
• NCBI ID: WP_005647998.1
• Uniprot ID: A0ABY1VSD0
• Organism: Haemophilus influenzae F3031
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1266245..1276919

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HIBPF_RS06400	-	1266245..1266643 (-)	399	WP_032826358.1	hypothetical protein	-
HIBPF_RS06405 (HIBPF13420)	-	1266654..1268639 (-)	1986	WP_013526171.1	Mu transposase C-terminal domain-containing protein	-
HIBPF_RS06410	-	1268683..1268961 (-)	279	WP_041174962.1	helix-turn-helix domain-containing protein	-
HIBPF_RS06415 (HIBPF13430)	-	1269137..1269853 (+)	717	WP_013526172.1	helix-turn-helix transcriptional regulator	-
HIBPF_RS10490	-	1270234..1270401 (-)	168	WP_158305134.1	hypothetical protein	-
HIBPF_RS06420 (HIBPF_13440)	rumB	1270446..1270880 (+)	435	Protein_1270	23S rRNA (uracil(747)-C(5))-methyltransferase	-
HIBPF_RS06425 (HIBPF13450)	crp	1271245..1271919 (-)	675	WP_005647998.1	cAMP-activated global transcriptional regulator CRP	Regulator
HIBPF_RS06430 (HIBPF13460)	-	1271904..1272155 (-)	252	WP_005647999.1	YheU family protein	-
HIBPF_RS06435 (HIBPF13470)	slmA	1272177..1272833 (-)	657	WP_005648000.1	nucleoid occlusion factor SlmA	-
HIBPF_RS06440 (HIBPF13480)	dut	1272837..1273292 (-)	456	WP_005631431.1	dUTP diphosphatase	-
HIBPF_RS06445 (HIBPF13490)	coaBC	1273340..1274542 (-)	1203	WP_011272308.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
HIBPF_RS06450 (HIBPF13500)	radC	1274705..1275370 (+)	666	WP_013526173.1	RadC family protein	Machinery gene
HIBPF_RS06455 (HIBPF13510)	rpmB	1275584..1275820 (+)	237	WP_005542826.1	50S ribosomal protein L28	-
HIBPF_RS06460 (HIBPF13520)	rpmG	1275832..1276002 (+)	171	WP_005613503.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25151.85 Da
• Isoelectric Point: 6.8375

>NTDB_id=33202 HIBPF_RS06425 WP_005647998.1 1271245..1271919(-) (crp) [Haemophilus influenzae F3031]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide

• Length: 675 bp

>NTDB_id=33202 HIBPF_RS06425 WP_005647998.1 1271245..1271919(-) (crp) [Haemophilus influenzae F3031]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGA
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterProScan.

• Cyclic nucleotide-binding domain (cNMP_binding) (36-124)

• Crp-like helix-turn-helix domain (HTH_Crp_2) (156-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Haemophilus influenzae Rd KW20	100	100	1
crp	Vibrio cholerae strain A1552	75.49	91.071	0.687
crp	Acinetobacter baumannii D1279779	48.705	86.161	0.42