Detailed information    

insolico Bioinformatically predicted

Overview

Name   tfoX   Type   Regulator
Locus tag   EKH72_RS06250 Genome accession   NZ_CP034565
Coordinates   1260966..1261553 (+) Length   195 a.a.
NCBI ID   WP_005459593.1    Uniprot ID   Q87QA8
Organism   Vibrio parahaemolyticus strain D3112     
Function   master regulator of natural competence (predicted from homology)   
Competence regulation

Genomic Context

Location: 1255966..1266553
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EKH72_RS06220 panP 1256135..1257781 (-) 1647 WP_129829981.1 pyridoxal-dependent aspartate 1-decarboxylase PanP -
  EKH72_RS06225 - 1257942..1258454 (-) 513 WP_005485575.1 hypothetical protein -
  EKH72_RS06230 - 1258662..1259567 (-) 906 WP_005483516.1 lysine exporter LysO family protein -
  EKH72_RS06235 - 1259675..1260595 (-) 921 WP_020840442.1 HDOD domain-containing protein -
  EKH72_RS06250 tfoX 1260966..1261553 (+) 588 WP_005459593.1 TfoX/Sxy family DNA transformation protein Regulator
  EKH72_RS06255 - 1261726..1262271 (-) 546 WP_005459590.1 hypothetical protein -
  EKH72_RS06260 - 1262469..1262966 (-) 498 WP_020840443.1 response regulator -
  EKH72_RS06265 - 1262963..1264903 (-) 1941 WP_129829982.1 ATP-binding protein -
  EKH72_RS06270 - 1265090..1266355 (+) 1266 WP_129829983.1 DUF945 family protein -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22459.81 Da        Isoelectric Point: 7.0628

>NTDB_id=331940 EKH72_RS06250 WP_005459593.1 1260966..1261553(+) (tfoX) [Vibrio parahaemolyticus strain D3112]
MDMTDQAFFKYVRNFNEYQKRSMFGGIGLFSDDAMFALVSNDCCYLRGGNGLDEEFTLLNCEKYKHVKKQTTATVNYYDV
TDLFESGFTGLDDLLRKSIDCSIKERKYQKSSASKRLRDLPNMQLTLERMVKKAGIDDVETFLELGPVEVFNKVRVAYGN
DVDVKLLWKFAGAIDGVHWKLIQEPRKKQLLALCE

Nucleotide


Download         Length: 588 bp        

>NTDB_id=331940 EKH72_RS06250 WP_005459593.1 1260966..1261553(+) (tfoX) [Vibrio parahaemolyticus strain D3112]
ATGGACATGACAGACCAAGCTTTTTTTAAATATGTACGCAATTTTAATGAGTATCAGAAACGTTCTATGTTTGGTGGTAT
CGGCTTGTTTAGCGATGACGCCATGTTTGCGCTTGTCAGCAATGATTGCTGTTATTTGCGCGGCGGTAATGGTTTAGACG
AAGAATTTACTCTGCTTAATTGTGAAAAATACAAGCACGTCAAAAAACAGACGACGGCTACTGTAAACTATTATGACGTA
ACCGATTTATTTGAGTCCGGATTTACTGGCCTTGACGATTTGTTACGCAAATCTATTGATTGCTCAATTAAGGAGCGAAA
ATACCAAAAGTCTTCTGCAAGTAAACGTTTGAGAGATCTACCGAACATGCAGCTTACATTAGAGCGCATGGTTAAAAAGG
CGGGTATTGATGATGTTGAAACCTTTTTGGAACTTGGTCCAGTTGAAGTGTTCAACAAAGTAAGAGTTGCTTACGGCAAT
GATGTTGACGTTAAACTGCTGTGGAAGTTTGCTGGTGCCATTGATGGTGTGCATTGGAAACTAATCCAAGAGCCGCGCAA
AAAACAGTTACTGGCACTGTGTGAATAA

Domains

Predicted by InterproScan.

TfoX N-terminal domain (TfoX_N)

(11-101)

TfoX C-terminal domain (TfoX_C)

(114-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q87QA8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  tfoX Vibrio parahaemolyticus RIMD 2210633

100

100

1
  tfoX Vibrio campbellii strain DS40M4

91.795

100

0.918
  tfoX Vibrio cholerae O1 biovar El Tor str. N16961

68.394

98.974

0.677
  tfoX Vibrio cholerae O1 biovar El Tor strain DRC-193A

68.394

98.974

0.677
  tfoX Vibrio cholerae O1 biovar El Tor strain P27459

68.394

98.974

0.677
  tfoX Vibrio cholerae O1 biovar El Tor strain E7946

68.394

98.974

0.677
  tfoX Vibrio cholerae strain A1552

68.394

98.974

0.677
  tfoX Aliivibrio fischeri ES114

57.068

97.949

0.559

Multiple sequence alignment