Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   EHW89_RS02065 Genome accession   NZ_CP034543
Coordinates   413720..415021 (+) Length   433 a.a.
NCBI ID   WP_126466534.1    Uniprot ID   A0A3Q9F1X5
Organism   Streptococcus periodonticum strain KCOM 2412     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 408720..420021
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHW89_RS02050 (EHW89_02050) - 410915..411844 (+) 930 Protein_361 IS3 family transposase -
  EHW89_RS02055 (EHW89_02055) cysK 412000..412929 (-) 930 WP_126466533.1 cysteine synthase A -
  EHW89_RS02060 (EHW89_02060) - 413028..413663 (-) 636 WP_115233548.1 YigZ family protein -
  EHW89_RS02065 (EHW89_02065) comFA/cflA 413720..415021 (+) 1302 WP_126466534.1 DEAD/DEAH box helicase Machinery gene
  EHW89_RS02070 (EHW89_02070) - 415018..415683 (+) 666 WP_049507482.1 ComF family protein -
  EHW89_RS02075 (EHW89_02075) hpf 415762..416304 (+) 543 WP_003025754.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  EHW89_RS02080 (EHW89_02080) rsmD 416492..417040 (+) 549 WP_193552987.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  EHW89_RS02085 (EHW89_02085) coaD 417030..417527 (+) 498 WP_126466536.1 pantetheine-phosphate adenylyltransferase -
  EHW89_RS02090 (EHW89_02090) sepM 417508..418563 (+) 1056 WP_126466537.1 SepM family pheromone-processing serine protease Regulator
  EHW89_RS02095 (EHW89_02095) - 418701..419264 (+) 564 WP_126466538.1 YutD family protein -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49171.95 Da        Isoelectric Point: 8.3845

>NTDB_id=331767 EHW89_RS02065 WP_126466534.1 413720..415021(+) (comFA/cflA) [Streptococcus periodonticum strain KCOM 2412]
MTELQDCLGRIFTQNQLSPELQLQAQSLAGMVEEKGKLSCNRCGQAIDKEKHQLPIGAYYCRSCLILGRVRSDEELYYFP
QEEFPKANVLKWQGKLTAFQAKVSQGLVEAVTKRKDSLVHAVTGAGKTEMIYQVVAQVINQGGAVCLASPRIDVCLELYR
RLKEDFDCNISLLHGESEAYSRSPLVIATTHQLLKFYRAFDLLIVDEVDAFPYVDNPMLYHAVHQAVKVEGTKIFLTATS
TDELDKKVAKGELTRLSLPRRFHGNPLIVPRKVWLENFQKYLNQKKLVPKLRQFIQKQRKTEFPFLIFASEIKRGQELAE
ILQSTFPNEKVGFVASTTENRLEIVEKFRQKEITILVTTTILERGVTFPCVDVFVVEANHRLFSRSALVQIAGRVGRSME
RPTGELIFFHDGATMAIEKAIKEIQEMNQEAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=331767 EHW89_RS02065 WP_126466534.1 413720..415021(+) (comFA/cflA) [Streptococcus periodonticum strain KCOM 2412]
ATGACGGAATTACAAGATTGTTTAGGTCGCATTTTTACCCAAAATCAACTGTCACCAGAATTGCAATTGCAAGCACAAAG
CTTAGCTGGAATGGTAGAAGAGAAAGGAAAGTTAAGCTGTAATCGCTGTGGACAAGCCATTGACAAAGAAAAACACCAAC
TGCCAATCGGTGCTTATTATTGTAGGTCTTGCTTGATCTTAGGAAGAGTTAGGAGTGATGAAGAACTATACTATTTTCCA
CAGGAAGAATTTCCCAAAGCGAATGTTTTGAAATGGCAAGGAAAGTTGACAGCATTTCAAGCCAAGGTTTCTCAAGGACT
TGTAGAGGCGGTTACCAAACGCAAAGATAGCTTGGTTCACGCAGTCACGGGAGCCGGAAAGACGGAAATGATCTATCAAG
TGGTGGCACAAGTCATCAATCAGGGCGGAGCAGTCTGCTTGGCTAGCCCCAGAATTGATGTCTGCTTAGAACTTTATCGC
AGACTGAAAGAAGATTTTGACTGTAACATTTCACTCTTGCACGGCGAATCAGAAGCATATTCCCGCAGTCCTCTCGTGAT
TGCCACCACACATCAGCTTCTCAAATTTTACCGAGCATTTGATCTTCTTATTGTTGATGAGGTAGATGCCTTTCCTTATG
TGGACAATCCGATGCTTTATCATGCAGTTCATCAGGCAGTCAAAGTAGAGGGGACGAAGATTTTCTTAACAGCAACTTCC
ACAGATGAGCTGGATAAAAAAGTAGCTAAAGGAGAATTAACTCGTTTGAGTCTACCCAGACGTTTTCATGGCAATCCTTT
GATTGTTCCTCGAAAAGTTTGGCTGGAAAATTTTCAAAAATACTTGAATCAAAAGAAGCTAGTTCCCAAGTTAAGGCAAT
TTATTCAAAAGCAAAGAAAAACAGAATTTCCATTTCTTATTTTTGCTTCCGAGATCAAAAGAGGGCAGGAGCTGGCAGAG
ATTCTTCAAAGCACTTTTCCTAATGAAAAAGTTGGCTTTGTAGCCTCGACGACTGAAAATCGGCTAGAAATTGTAGAGAA
ATTTCGTCAAAAAGAGATCACGATCTTAGTAACGACGACGATTTTGGAGCGTGGAGTGACTTTTCCTTGTGTAGATGTTT
TCGTAGTGGAAGCCAACCACCGTCTGTTTAGTCGTAGCGCTCTGGTACAAATTGCTGGACGCGTTGGTCGCAGTATGGAG
CGACCGACAGGCGAGTTAATCTTTTTTCATGACGGTGCGACTATGGCGATAGAAAAAGCGATTAAAGAAATTCAGGAGAT
GAATCAGGAGGCCGGTTTATGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(108-245)

Helicase conserved C-terminal domain (Helicase_C)

(291-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3Q9F1X5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

71.262

98.845

0.704
  comFA/cflA Streptococcus pneumoniae D39

71.262

98.845

0.704
  comFA/cflA Streptococcus pneumoniae R6

71.262

98.845

0.704
  comFA/cflA Streptococcus mitis NCTC 12261

71.362

98.383

0.702
  comFA/cflA Streptococcus pneumoniae TIGR4

71.028

98.845

0.702
  comFA/cflA Streptococcus mitis SK321

70.892

98.383

0.697
  comFA Lactococcus lactis subsp. cremoris KW2

55.025

91.917

0.506
  comFA Latilactobacillus sakei subsp. sakei 23K

40.371

99.538

0.402
  comFA Bacillus subtilis subsp. subtilis str. 168

40.741

93.533

0.381

Multiple sequence alignment