Detailed information NTG0331768

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EHW89_RS02090
• Genome accession: NZ_CP034543
• Coordinates: 417508..418563 (+)
• Length: 351 a.a.
• NCBI ID: WP_126466537.1
• Uniprot ID: A0A3S9MQ42
• Organism: Streptococcus periodonticum strain KCOM 2412
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 412508..423563

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EHW89_RS02060 (EHW89_02060)	-	413028..413663 (-)	636	WP_115233548.1	YigZ family protein	-
EHW89_RS02065 (EHW89_02065)	comFA/cflA	413720..415021 (+)	1302	WP_126466534.1	DEAD/DEAH box helicase	Machinery gene
EHW89_RS02070 (EHW89_02070)	-	415018..415683 (+)	666	WP_049507482.1	ComF family protein	-
EHW89_RS02075 (EHW89_02075)	hpf	415762..416304 (+)	543	WP_003025754.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
EHW89_RS02080 (EHW89_02080)	rsmD	416492..417040 (+)	549	WP_193552987.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EHW89_RS02085 (EHW89_02085)	coaD	417030..417527 (+)	498	WP_126466536.1	pantetheine-phosphate adenylyltransferase	-
EHW89_RS02090 (EHW89_02090)	sepM	417508..418563 (+)	1056	WP_126466537.1	SepM family pheromone-processing serine protease	Regulator
EHW89_RS02095 (EHW89_02095)	-	418701..419264 (+)	564	WP_126466538.1	YutD family protein	-
EHW89_RS02100 (EHW89_02100)	rlmN	419305..420387 (+)	1083	WP_024052079.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
EHW89_RS02105 (EHW89_02105)	-	420380..420910 (+)	531	WP_126466539.1	VanZ family protein	-
EHW89_RS02110 (EHW89_02110)	trpB	421271..422479 (+)	1209	WP_126466540.1	tryptophan synthase subunit beta	-
EHW89_RS02115 (EHW89_02115)	cclA/cilC	422640..423299 (-)	660	WP_126466541.1	A24 family peptidase	Machinery gene

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 38354.25 Da
• Isoelectric Point: 10.1140

>NTDB_id=331768 EHW89_RS02090 WP_126466537.1 417508..418563(+) (sepM) [Streptococcus periodonticum strain KCOM 2412]
MEKSRNKFKKWPIIAVVGLILLFLSFVVPLPYYIEVPGGAADVRQVLRVDNKEDKEKGSYNFVTVGIQHATFAHLVYAWL
TPFTDIYSAKDLTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDITLKYLGVYVLQVTKNSTFKGILNIADTVTGVN
DKTFNSSKELIDYVGAQKIGSKVKVNYVEDGQKKSATGKIIKLENGKNGIGISLIDRTEVTSNTPIEFSTAGIGGPSAGL
MFSLAIYTQIADPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNGAEIFFAPNNPVTKEAKKANPKAKTNYETAL
EAAKKIKTNMKIVPVKTLQDAIDYLKSTKKL

Nucleotide

• Length: 1056 bp

>NTDB_id=331768 EHW89_RS02090 WP_126466537.1 417508..418563(+) (sepM) [Streptococcus periodonticum strain KCOM 2412]
ATGGAAAAATCAAGAAATAAATTTAAAAAATGGCCGATAATTGCAGTAGTAGGGTTGATTTTGCTTTTCTTATCTTTTGT
AGTTCCCTTGCCTTATTATATTGAGGTGCCAGGTGGTGCAGCGGATGTCCGTCAGGTATTGCGCGTGGACAACAAAGAAG
ATAAGGAAAAAGGTTCTTATAATTTTGTAACGGTTGGAATTCAGCATGCGACCTTCGCTCATTTGGTTTATGCTTGGCTG
ACACCCTTTACGGATATTTATTCGGCGAAGGATTTGACTGGTGGAACTTCTGATAAAGAATACATGCGGATCAATCAGTT
TTATATGGAAACGTCGCAAAACCTAGCTAAATACCAAGGGTTGAAAAAAGCTGGCAAAGACATTACTCTGAAATATCTAG
GGGTTTACGTCTTGCAAGTCACAAAGAATTCTACTTTTAAAGGTATTTTAAATATTGCAGATACCGTGACAGGTGTGAAT
GATAAGACTTTCAATAGTTCAAAAGAATTGATAGACTATGTCGGCGCGCAAAAGATTGGCAGCAAGGTCAAGGTGAACTA
TGTAGAAGACGGTCAGAAGAAGTCTGCTACAGGTAAAATTATTAAACTTGAAAATGGGAAAAACGGGATTGGCATTAGTT
TGATTGACCGAACAGAAGTCACAAGCAACACACCAATTGAATTTTCAACTGCCGGTATTGGTGGACCAAGTGCGGGCTTG
ATGTTTAGTTTGGCAATTTATACGCAAATTGCAGATCCAACATTGAGAGACGGCAGAAATATTGCTGGGACAGGTTCGAT
TGACCGCGAAGGAAAAGTTGGCGACATTGGTGGGATTGACAAAAAAGTTGTTTCAGCAGCTAAAAATGGCGCAGAAATTT
TCTTTGCGCCAAATAATCCAGTTACCAAGGAAGCTAAAAAAGCTAATCCTAAAGCGAAAACCAACTATGAAACAGCTTTG
GAAGCTGCTAAAAAAATTAAGACTAATATGAAAATTGTACCCGTGAAAACTTTGCAAGACGCCATTGATTACCTCAAGAG
CACAAAGAAGTTGTAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (234-300)

• PDZ domain (PDZ_2) (133-197)

3D structure

• AlphaFold DB: A0A3S9MQ42

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	63.953	98.006	0.627