Detailed information NTG0033166

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: SPJ_RS08925
• Genome accession: NC_012466
• Coordinates: 1713034..1714101 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159555.1
• Uniprot ID: A0A0I8P776
• Organism: Streptococcus pneumoniae JJA
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1708034..1719101

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPJ_RS08900 (SPJ_1790)	treR	1708206..1708916 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
SPJ_RS08905 (SPJ_1791)	-	1708949..1709752 (-)	804	WP_000202632.1	ATP-binding cassette domain-containing protein	-
SPJ_RS08910 (SPJ_1792)	-	1709765..1710658 (-)	894	WP_001012092.1	ABC transporter permease	-
SPJ_RS08915 (SPJ_1793)	-	1710670..1711607 (-)	938	Protein_1701	ABC transporter substrate-binding protein	-
SPJ_RS13600 (SPJ_1795)	-	1711900..1712031 (-)	132	WP_000787593.1	hypothetical protein	-
SPJ_RS08920 (SPJ_1796)	amiF	1712097..1713023 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
SPJ_RS08925 (SPJ_1797)	amiE	1713034..1714101 (-)	1068	WP_000159555.1	ABC transporter ATP-binding protein	Regulator
SPJ_RS08930 (SPJ_1798)	amiD	1714110..1715036 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
SPJ_RS08935 (SPJ_1799)	amiC	1715036..1716532 (-)	1497	WP_000759903.1	ABC transporter permease	Regulator
SPJ_RS08940 (SPJ_1800)	amiA3	1716599..1718578 (-)	1980	WP_000742238.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39489.14 Da
• Isoelectric Point: 5.0389

>NTDB_id=33166 SPJ_RS08925 WP_000159555.1 1713034..1714101(-) (amiE) [Streptococcus pneumoniae JJA]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSKTHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=33166 SPJ_RS08925 WP_000159555.1 1713034..1714101(-) (amiE) [Streptococcus pneumoniae JJA]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCTT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAAAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A0I8P776

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541