Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   FGL73_RS11065 Genome accession   NZ_CP042408
Coordinates   2277125..2278567 (-) Length   480 a.a.
NCBI ID   WP_058206000.1    Uniprot ID   -
Organism   Lactococcus lactis strain CBA3619     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2272125..2283567
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL73_RS11040 (FGL73_11040) nox 2272160..2273500 (+) 1341 WP_098393171.1 H2O-forming NADH oxidase -
  FGL73_RS11045 (FGL73_11045) - 2273590..2273979 (+) 390 WP_038599186.1 single-stranded DNA-binding protein -
  FGL73_RS11050 (FGL73_11050) groES 2274099..2274383 (+) 285 WP_003131589.1 co-chaperone GroES -
  FGL73_RS11055 (FGL73_11055) groL 2274470..2276098 (+) 1629 WP_003131585.1 chaperonin GroEL -
  FGL73_RS11060 (FGL73_11060) vicX 2276142..2276954 (-) 813 WP_038599190.1 MBL fold metallo-hydrolase Regulator
  FGL73_RS11065 (FGL73_11065) vicK 2277125..2278567 (-) 1443 WP_058206000.1 cell wall metabolism sensor histidine kinase WalK Regulator
  FGL73_RS11070 (FGL73_11070) yycF 2278560..2279261 (-) 702 WP_038599193.1 response regulator YycF -
  FGL73_RS11075 (FGL73_11075) tmk 2279439..2280074 (+) 636 WP_038599196.1 dTMP kinase -
  FGL73_RS11080 (FGL73_11080) - 2280207..2281067 (+) 861 WP_038599199.1 DNA polymerase III subunit delta' -
  FGL73_RS11085 (FGL73_11085) yaaT 2281119..2281901 (+) 783 WP_038599202.1 stage 0 sporulation family protein Regulator
  FGL73_RS11090 (FGL73_11090) yabA 2281894..2282220 (+) 327 WP_003131570.1 DNA replication initiation control protein YabA -
  FGL73_RS11095 (FGL73_11095) rsmI 2282220..2283095 (+) 876 WP_038599205.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  FGL73_RS11100 (FGL73_11100) - 2283172..2283363 (-) 192 WP_012897234.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54636.07 Da        Isoelectric Point: 4.5625

>NTDB_id=331635 FGL73_RS11065 WP_058206000.1 2277125..2278567(-) (vicK) [Lactococcus lactis strain CBA3619]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMEKNIVE
VLKIEDQYNFYDLLEKEPEVTIETHDTGNEAISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSDGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEGNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=331635 FGL73_RS11065 WP_058206000.1 2277125..2278567(-) (vicK) [Lactococcus lactis strain CBA3619]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCCCACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATCGGTTACTACCTATTTTCACTCGTCTTTGTTTTAGTCTTTCTTA
ATCAGCAGCATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGTGATAAAATC
CCAAAAGGGACAAGTGAAATCAATGAATTATACGACGAAATTTTAAAACTTGGTGAAGATATTGTTCGCACTCAGAACAA
TCTTGAAAATCAGAGAAATCAATTAGACAGCATCCTCGCCTATATGGTTGATGGCGTCATTGCCACCGACCGTCGCGGGA
ATATTATTATGGCCAATAAATCAGCTTTGCATTATTTGAATACAGATAATGATCTCTTGATGGAAAAAAATATTGTTGAG
GTCTTAAAAATTGAAGACCAGTATAATTTCTATGATTTATTGGAAAAGGAGCCAGAGGTAACTATTGAAACACATGATAC
TGGAAATGAAGCCATTTCACTTCACATAAAATTTGCTCTTTTTCGTCGTGAGTCTGGTTTTATTTCAGGAATTATTGCTG
TTTTACATGATATGACTGAACAAGATAAAGCAGAACGTGAACGACGCCTATTTGTTTCTAATGTTTCACACGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACTCTCGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAACGCAATTAAGTATTCCCCTAAAGGTGGAACGATTA
CAATTTCCGTTGAAAAACGTGAAAGTGACGTTCTAATCTCCATCAGTGACCAAGGAATGGGAATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGATAACGCTTCAAGAAATTCAAAAGTTGGGGGAACAGGTTTAGGCCTCTC
TATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGCTCTGATGGAGAAGGAAAAGGAACAACCTTTA
GTTTCACTCTTCCATATTCTTTAGAAGCCGCAGATGACTGGGATGATGGCACTGATGAGTTTGAATTTGAGGGTAATGAA
TAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

PAS domain (PAS_9)

(124-220)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.319

86.875

0.446
  micB Streptococcus pneumoniae Cp1015

47.748

92.5

0.442