Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   EIA51_RS02565 Genome accession   NZ_CP034110
Coordinates   480381..481703 (+) Length   440 a.a.
NCBI ID   WP_035688106.1    Uniprot ID   -
Organism   Avibacterium paragallinarum strain FARPER-174     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 475381..486703
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EIA51_RS02540 (EIA51_02540) - 475482..478031 (-) 2550 WP_035688097.1 penicillin-binding protein 1A -
  EIA51_RS02545 (EIA51_02545) - 478190..478957 (+) 768 WP_035688099.1 hypothetical protein -
  EIA51_RS02550 (EIA51_02550) - 478987..479499 (+) 513 WP_046097217.1 PilN domain-containing protein -
  EIA51_RS02555 (EIA51_02555) - 479492..480013 (+) 522 WP_124994794.1 hypothetical protein -
  EIA51_RS02560 (EIA51_02560) - 480013..480372 (+) 360 WP_017806828.1 hypothetical protein -
  EIA51_RS02565 (EIA51_02565) comE 480381..481703 (+) 1323 WP_035688106.1 type IV pilus secretin PilQ Machinery gene
  EIA51_RS02570 (EIA51_02570) aroK 481937..482464 (+) 528 WP_035688108.1 shikimate kinase AroK -
  EIA51_RS02575 (EIA51_02575) aroB 482481..483569 (+) 1089 WP_035688110.1 3-dehydroquinate synthase -
  EIA51_RS02580 (EIA51_02580) - 483575..484465 (+) 891 WP_035688112.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  EIA51_RS02585 (EIA51_02585) - 484437..484742 (-) 306 WP_035688115.1 DciA family protein -
  EIA51_RS02590 (EIA51_02590) secM 484848..485159 (+) 312 WP_035688161.1 secA translation cis-regulator SecM -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 48606.59 Da        Isoelectric Point: 6.1204

>NTDB_id=329082 EIA51_RS02565 WP_035688106.1 480381..481703(+) (comE) [Avibacterium paragallinarum strain FARPER-174]
MKLPNIIKNILLFFLILSYPFRQVNASDENNTFSVHLKQAPLVDTVQYLAGYQKINLVIDDELSGSISLQLQNTTLLQLL
KSIAEIKHLRFWENNGIYYLSQSQATNQENVVLNSSTEIATSADMLITSIKLHYAKASEVMKALTSGNGSLLTANGSISF
DERNNLLIIQDEAKKIKQIRKLVADMDKPIQQIIIEARIVTISDESLKELGVRWGIFSPSDISHSVSGSLNANGFSNITD
NLNINFATSSNPAGSVALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVNNGKNDTQSIE
FREAVLGLEVTPHLLKHNGILLDLVVSQNAPGGRVSYGENEVISIDKQEINTQVFAQDGETIVLGGIFHDTITKALDKVP
ILGDIPGIKRLFSKEVERHQKRELVIFVTPRLIRSGTVEE

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=329082 EIA51_RS02565 WP_035688106.1 480381..481703(+) (comE) [Avibacterium paragallinarum strain FARPER-174]
ATGAAGTTACCAAATATAATAAAGAATATTCTTTTATTTTTTCTTATTCTATCCTATCCATTTAGACAGGTTAATGCAAG
TGACGAAAATAATACATTCTCTGTTCATTTAAAGCAGGCTCCATTAGTAGATACTGTACAATATTTAGCTGGGTATCAAA
AAATCAATTTAGTCATAGATGATGAATTGTCTGGTTCAATATCTTTGCAATTGCAAAATACAACATTACTTCAATTATTA
AAATCTATCGCTGAAATCAAACATTTGCGGTTTTGGGAAAATAATGGGATATATTATTTAAGTCAGTCGCAAGCAACTAA
TCAAGAAAATGTAGTGTTAAATTCATCAACAGAAATAGCAACATCAGCAGATATGTTAATAACTTCAATAAAGTTGCACT
ATGCCAAAGCATCCGAGGTAATGAAAGCCCTCACTTCAGGGAATGGCTCTTTATTAACAGCAAATGGAAGTATAAGTTTT
GATGAACGCAATAATTTACTCATTATCCAAGATGAAGCTAAAAAAATAAAACAAATTAGGAAATTGGTAGCGGATATGGA
TAAACCCATTCAGCAAATTATTATTGAAGCTCGTATTGTCACAATTAGCGATGAAAGTTTAAAAGAATTGGGAGTCAGAT
GGGGAATTTTTTCTCCCTCAGATATAAGCCATAGCGTTTCTGGAAGTTTAAATGCAAATGGATTCTCAAATATTACGGAT
AATCTAAATATTAATTTTGCGACGAGTTCAAATCCTGCAGGTTCGGTAGCTTTGCAAGTAGCTAAAATTAATGGAAGGTT
ATTAGATTTAGAGTTGACAGCATTAGAAAGAGAAAATAACGTTGAAATTATTGCGAGTCCACGATTATTGACCACAAATA
AGAAAAGTGCAAGTATCAAGCAAGGTACAGAAATCCCCTATGTAGTGAATAATGGAAAAAATGATACGCAGTCTATTGAA
TTCCGAGAAGCTGTACTTGGGCTTGAAGTTACACCTCATTTATTAAAGCATAACGGTATTTTACTTGATCTTGTTGTTAG
TCAGAATGCACCTGGAGGACGAGTATCTTATGGAGAAAATGAGGTGATTTCTATTGATAAACAGGAAATTAATACGCAAG
TCTTTGCACAAGACGGCGAAACGATTGTATTGGGCGGAATTTTCCACGATACGATTACTAAAGCACTTGATAAAGTACCA
ATTTTAGGAGACATACCTGGAATAAAAAGGCTATTTAGTAAGGAAGTCGAGAGACATCAAAAGAGGGAACTCGTTATTTT
TGTTACACCACGCTTAATTCGTAGTGGTACAGTAGAGGAATGA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(129-192)

Bacterial type II and III secretion system protein (Secretin)

(274-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

65.023

96.818

0.63
  comE Haemophilus influenzae 86-028NP

64.789

96.818

0.627
  comE Glaesserella parasuis strain SC1401

49.883

97.045

0.484
  pilQ Vibrio campbellii strain DS40M4

40

96.591

0.386
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

40.288

94.773

0.382
  pilQ Vibrio cholerae strain A1552

40.288

94.773

0.382

Multiple sequence alignment