Detailed information NTG0032731

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: HMPREF0837_RS10915
• Genome accession: NC_014251
• Coordinates: 2066591..2067490 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904848.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae TCH8431/19A
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 2061591..2072490

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF0837_RS10900 (HMPREF0837_12253)	rsmA	2062241..2063113 (-)	873	WP_001216856.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
HMPREF0837_RS13135	-	2063364..2063657 (-)	294	Protein_2063	hypothetical protein	-
HMPREF0837_RS10905 (HMPREF0837_12256)	-	2063650..2064291 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
HMPREF0837_RS10910 (HMPREF0837_12257)	-	2064293..2066323 (-)	2031	WP_000825271.1	bacteriocin-associated integral membrane family protein	-
HMPREF0837_RS10915 (HMPREF0837_12258)	comR	2066591..2067490 (-)	900	WP_000904848.1	helix-turn-helix transcriptional regulator	Regulator
HMPREF0837_RS10920 (HMPREF0837_12259)	rnmV	2067562..2068122 (-)	561	WP_000660013.1	ribonuclease M5	-
HMPREF0837_RS10925 (HMPREF0837_12260)	-	2068122..2068895 (-)	774	WP_000575650.1	TatD family hydrolase	-
HMPREF0837_RS10930 (HMPREF0837_12261)	-	2069200..2070171 (-)	972	Protein_2069	DUF1542 domain-containing protein	-
HMPREF0837_RS10935 (HMPREF0837_12262)	rpmH	2070377..2070511 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
HMPREF0837_RS10940 (HMPREF0837_12263)	-	2070656..2071870 (-)	1215	WP_000666484.1	pyridoxal phosphate-dependent aminotransferase	-
HMPREF0837_RS10945	-	2072026..2072318 (-)	293	Protein_2072	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35420.14 Da
• Isoelectric Point: 4.6674

>NTDB_id=32731 HMPREF0837_RS10915 WP_000904848.1 2066591..2067490(-) (comR) [Streptococcus pneumoniae TCH8431/19A]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
IRLFFYQMLIRKDLAKFINQIEELMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=32731 HMPREF0837_RS10915 WP_000904848.1 2066591..2067490(-) (comR) [Streptococcus pneumoniae TCH8431/19A]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTCCTGCTTATTTAGAATTGAAATATCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAGAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus pyogenes MGAS8232	36.577	99.666	0.365
comR	Streptococcus pyogenes MGAS315	36	100	0.361
comR	Streptococcus suis P1/7	37.113	97.324	0.361
comR	Streptococcus suis 05ZYH33	37.113	97.324	0.361