Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   EHF40_RS01405 Genome accession   NZ_CP033907
Coordinates   257328..259307 (+) Length   659 a.a.
NCBI ID   WP_021299351.1    Uniprot ID   A0A660A5X6
Organism   Streptococcus pyogenes strain Duke-Large     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 252328..264307
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHF40_RS01385 (EHF40_01385) sufU 252374..252853 (+) 480 WP_011528251.1 Fe-S cluster assembly sulfur transfer protein SufU -
  EHF40_RS01390 (EHF40_01390) sufB 252846..254264 (+) 1419 WP_002986015.1 Fe-S cluster assembly protein SufB -
  EHF40_RS01395 (EHF40_01395) - 254416..255597 (-) 1182 WP_011528252.1 serine hydrolase -
  EHF40_RS01400 (EHF40_01400) pbp3 255765..256997 (-) 1233 WP_021299357.1 D-alanyl-D-alanine carboxypeptidase PBP3 -
  EHF40_RS01405 (EHF40_01405) amiA 257328..259307 (+) 1980 WP_021299351.1 peptide ABC transporter substrate-binding protein Regulator
  EHF40_RS01410 (EHF40_01410) amiC 259372..260874 (+) 1503 WP_011017334.1 ABC transporter permease Regulator
  EHF40_RS01415 (EHF40_01415) amiD 260874..261800 (+) 927 WP_002986004.1 oligopeptide ABC transporter permease OppC Regulator
  EHF40_RS01420 (EHF40_01420) amiE 261809..262879 (+) 1071 WP_010921893.1 ABC transporter ATP-binding protein Regulator
  EHF40_RS01425 (EHF40_01425) amiF 262872..263795 (+) 924 WP_002986000.1 ABC transporter ATP-binding protein Regulator

Sequence

Protein


Download         Length: 659 a.a.        Molecular weight: 72426.97 Da        Isoelectric Point: 5.1964

>NTDB_id=326898 EHF40_RS01405 WP_021299351.1 257328..259307(+) (amiA) [Streptococcus pyogenes strain Duke-Large]
MKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVNDPKSLDYILTNGGGTTDVITQMVDGLLENDEYGNLV
PSLAKDWKVSKDGLTYTYTLRDGVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEV
GVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGAYFLSAFTSKSSMEFHKNENYWD
AKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARLYPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKNTKK
DPAQQDAGKKALNNKDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTVGESDFGSEVEKEMAKLGDEWKDVN
LADAQDGFYNPEKAKVEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQEAQSFKQSVEASLGKENVIVNVLETETSTHE
AQGFYAETPEQQDYDIISSWWGPDYQDPRTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAITDDN
DARYKAYAKAQAYLTDSAVDIPVVALGGTPRVTKAVPFSGAFAWAGAKGPASVYYYKGMKLQDKPVTAKQFEKAKEKWMK
AKAKSNAKYAEKLADHVEK

Nucleotide


Download         Length: 1980 bp        

>NTDB_id=326898 EHF40_RS01405 WP_021299351.1 257328..259307(+) (amiA) [Streptococcus pyogenes strain Duke-Large]
ATGAAGAAAAGTAAATGGTTGGCAGCTGTAAGTGTTGCGATCTTGTCAGTATCCGCTTTGGCAGCTTGTGGTAATAAAAA
TGCTTCAGGTGGCTCAGAAGCTACAAAAACCTACAAGTACGTTTTTGTTAACGATCCAAAATCATTGGATTATATTTTGA
CTAATGGCGGTGGAACGACTGATGTGATAACACAAATGGTTGATGGTCTTTTGGAAAACGATGAGTATGGTAATTTAGTA
CCATCACTTGCTAAAGATTGGAAGGTTTCAAAAGACGGTCTGACTTATACTTATACTCTTCGCGATGGTGTCTCTTGGTA
TACGGCTGATGGTGAAGAATATGCCCCAGTAACAGCAGAAGATTTTGTGACTGGTTTGAAGCACGCGGTTGACGATAAAT
CAGATGCTCTTTACGTTGTTGAAGATTCAATAAAAAACTTAAAGGCTTACCAAAATGGTGAAGTAGATTTTAAAGAAGTT
GGTGTCAAAGCCCTTGACGATAAAACTGTTCAGTATACTTTGAACAAGCCTGAAAGCTACTGGAATTCAAAAACAACTTA
TAGTGTGCTTTTCCCAGTTAATGCGAAATTTTTGAAGTCAAAAGGTAAAGATTTTGGTACAACCGATCCATCATCAATCC
TTGTTAATGGTGCTTACTTCTTGAGCGCCTTCACCTCAAAATCATCTATGGAATTCCATAAAAATGAAAACTACTGGGAT
GCTAAGAATGTTGGGATAGAATCTGTTAAATTGACTTACTCAGATGGTTCAGACCCAGGTTCGTTCTACAAGAACTTTGA
CAAGGGTGAGTTCAGCGTTGCACGACTTTACCCAAATGACCCTACCTACAAATCAGCTAAGAAAAACTATGCTGATAACA
TTACTTACGGAATGTTGACTGGAGATATCCGTCATTTAACATGGAATTTGAACCGTACTTCTTTCAAAAACACTAAGAAA
GACCCTGCACAACAAGATGCCGGTAAGAAAGCTCTTAACAACAAGGATTTTCGTCAAGCTATTCAATTTGCTTTTGACCG
AGCGTCATTCCAAGCACAAACTGCAGGTCAAGATGCCAAAACAAAAGCCTTACGTAACATGCTTGTGCCACCAACTTTTG
TAACCGTTGGAGAAAGTGATTTTGGTTCAGAAGTTGAAAAGGAAATGGCAAAACTTGGTGATGAATGGAAAGACGTTAAC
TTAGCTGATGCTCAAGATGGTTTCTATAATCCAGAAAAAGCAAAAGTTGAATTTGCAAAAGCCAAAGAAGCTTTGACAGC
TGAAGGTGTAACCTTCCCAGTTCAATTAGATTACCCTGTTGACCAGGCAAACGCAGCAACTGTTCAGGAAGCCCAGTCTT
TCAAACAATCTGTTGAAGCATCTCTTGGTAAAGAAAATGTCATTGTCAATGTTCTTGAAACAGAAACATCAACTCACGAA
GCCCAAGGCTTCTATGCTGAGACCCCAGAACAACAAGACTACGATATCATTTCATCATGGTGGGGACCAGACTACCAAGA
TCCACGGACCTACCTTGACATCATGAGTCCAGTAGGTGGTGGATCTGTTATCCAAAAACTTGGAATCAAAGCAGGTCAAA
ATAAGGATGTTGTGGCAGCTGCAGGCCTTGATACTTACCAAACTCTTCTTGATGAAGCAGCAGCAATTACAGACGACAAC
GATGCGCGCTATAAAGCTTACGCAAAAGCACAAGCCTACCTTACAGATAGTGCCGTAGATATTCCAGTTGTGGCATTGGG
TGGCACTCCTCGAGTTACTAAAGCCGTTCCATTTAGCGGTGCCTTTGCCTGGGCAGGTGCTAAAGGTCCTGCTTCTGTAT
ATTATTATAAAGGAATGAAACTTCAAGACAAACCTGTCACAGCAAAACAATTCGAAAAAGCAAAAGAAAAATGGATGAAA
GCAAAGGCTAAGTCAAATGCAAAATATGCTGAGAAGTTAGCTGATCACGTTGAAAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(79-515)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A660A5X6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

51.131

100

0.514
  amiA3 Streptococcus thermophilus LMG 18311

50.226

100

0.505
  amiA3 Streptococcus thermophilus LMD-9

49.925

100

0.502

Multiple sequence alignment