Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   HMPREF0837_RS01565 Genome accession   NC_014251
Coordinates   286082..286318 (+) Length   78 a.a.
NCBI ID   WP_000939544.1    Uniprot ID   -
Organism   Streptococcus pneumoniae TCH8431/19A     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 281082..291318
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0837_RS11225 - 284775..284984 (+) 210 Protein_278 transposase -
  HMPREF0837_RS11230 - 285019..285816 (-) 798 Protein_279 transposase -
  HMPREF0837_RS01565 (HMPREF0837_10307) comW 286082..286318 (+) 237 WP_000939544.1 sigma(X)-activator ComW Regulator
  HMPREF0837_RS01570 (HMPREF0837_10308) - 286549..287835 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  HMPREF0837_RS01575 (HMPREF0837_10309) tadA 288036..288503 (+) 468 WP_000291879.1 tRNA adenosine(34) deaminase TadA -
  HMPREF0837_RS01580 (HMPREF0837_10310) - 288690..289133 (+) 444 WP_000701992.1 dUTP diphosphatase -
  HMPREF0837_RS01585 (HMPREF0837_10311) - 289135..289650 (+) 516 WP_000691236.1 histidine phosphatase family protein -
  HMPREF0837_RS01590 (HMPREF0837_10312) radA 289664..291025 (+) 1362 WP_073076903.1 DNA repair protein RadA Machinery gene

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9667.10 Da        Isoelectric Point: 6.4701

>NTDB_id=32649 HMPREF0837_RS01565 WP_000939544.1 286082..286318(+) (comW) [Streptococcus pneumoniae TCH8431/19A]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=32649 HMPREF0837_RS01565 WP_000939544.1 286082..286318(+) (comW) [Streptococcus pneumoniae TCH8431/19A]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCATAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

97.436

100

0.974
  comW Streptococcus pneumoniae D39

97.436

100

0.974
  comW Streptococcus pneumoniae R6

97.436

100

0.974
  comW Streptococcus pneumoniae TIGR4

97.436

100

0.974
  comW Streptococcus mitis SK321

78.205

100

0.782
  comW Streptococcus mitis NCTC 12261

77.922

98.718

0.769

Multiple sequence alignment