Detailed information NTG0326099

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: EGX82_RS01490
• Genome accession: NZ_CP033822
• Coordinates: 310060..312297 (-)
• Length: 745 a.a.
• NCBI ID: WP_000939916.1
• Uniprot ID: A0AAW6XU20
• Organism: Streptococcus agalactiae strain FDAARGOS_512
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 305060..317297

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGX82_RS01465 (EGX82_01465)	holA	305124..306161 (-)	1038	WP_000560292.1	DNA polymerase III subunit delta	-
EGX82_RS01470 (EGX82_01470)	-	306215..306943 (-)	729	WP_000468965.1	methyltransferase domain-containing protein	-
EGX82_RS01475 (EGX82_01475)	-	307119..308111 (+)	993	WP_000800994.1	alpha/beta hydrolase	-
EGX82_RS01480 (EGX82_01480)	-	308170..309114 (-)	945	WP_000200825.1	LacI family DNA-binding transcriptional regulator	-
EGX82_RS01485 (EGX82_01485)	-	309125..309934 (-)	810	WP_000153219.1	Cof-type HAD-IIB family hydrolase	-
EGX82_RS01490 (EGX82_01490)	comEC/celB	310060..312297 (-)	2238	WP_000939916.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EGX82_RS01495 (EGX82_01495)	-	312281..312934 (-)	654	WP_000461744.1	helix-hairpin-helix domain-containing protein	-
EGX82_RS01500 (EGX82_01500)	-	313032..313772 (-)	741	WP_000500220.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
EGX82_RS01505 (EGX82_01505)	-	313907..314671 (+)	765	WP_000567423.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
EGX82_RS01510 (EGX82_01510)	-	314664..314930 (+)	267	WP_000598736.1	GIY-YIG nuclease family protein	-
EGX82_RS01515 (EGX82_01515)	-	315115..316701 (-)	1587	WP_000673088.1	DEAD/DEAH box helicase	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 85548.47 Da
• Isoelectric Point: 9.7741

>NTDB_id=326099 EGX82_RS01490 WP_000939916.1 310060..312297(-) (comEC/celB) [Streptococcus agalactiae strain FDAARGOS_512]
MLQLTKYFPLKPIYLALLVFQIYLLVFSWTMLGCAFLLFTFIFLIYQYDRETIFKTIAIVIFFLFYFLWQNHNMNVQYQR
VPNHISQIKVRIDTISINGDVLSFQADASGNTYQAFYTLKNKSEKDYFQNLDNNIMIIADIKLEEAEERRHFNGFDYRQY
LKRHGIYRIAKVTKIKQIRLFQHRSFFDLMFKWRRSAIVISQTFPNPMRHYMSGLLFGYLDKTFDDMSDLYSSLGIIHLF
ALSGMQVGFFLGIFRYICLRIGLRLDHVWLLQIPFSLIYAGLTGFSISVVRALIQSLLSHSGVKKDENFALCLLICLISL
PHSLLTTGGVLSFAYAFILTMTSFDHFSSIKKVAIESLTVSVGILPILTYYFSGFQPISIILTALLSFAFDIIFLPLLTV
IFVLSPIVKLGCINSLFEILEVLLKWTGQLFPRPLIFGKPSLFLLIVMIIILGLLYDYYHSKCFRYCSLLIIFTLFFITK
NPITNEVAILDVGQGDSILVRDWLGKTILIDTGGRVRFEQPEEWKQKVNQSNAERTLIPYLKSRGISKIDDLVITHTDTD
HMGDMEVISKHFKVARLITSSGSLTNSQYVKRLSKIGVAVKSIEAGDKLAVMGSYLQVLYPWHKGDGKNNDSIVLYGHLL
GKGFLFTGDLEEEGEKQLLEAYPNLSVDILKAGHHGSKGSSSLSFLKKLSPSVVLVSAGKNNRYQHPHQETLQRFQKIKS
KIFRTDQSGTIRLTGWWKWHIQTVR

Nucleotide

• Length: 2238 bp

>NTDB_id=326099 EGX82_RS01490 WP_000939916.1 310060..312297(-) (comEC/celB) [Streptococcus agalactiae strain FDAARGOS_512]
ATGTTACAATTGACTAAGTATTTTCCTCTAAAACCTATTTATTTAGCATTGTTGGTCTTCCAAATTTACTTACTAGTGTT
TTCTTGGACAATGCTTGGTTGTGCCTTTCTTTTATTTACTTTTATTTTTCTGATTTATCAATATGATCGTGAAACTATTT
TTAAAACAATAGCAATAGTAATTTTTTTCTTATTTTATTTTTTATGGCAAAATCACAATATGAATGTCCAATATCAAAGA
GTACCGAATCATATTAGCCAGATTAAAGTGCGTATTGATACTATTTCTATCAATGGTGATGTTTTATCATTCCAGGCAGA
TGCTTCAGGTAACACTTATCAAGCTTTTTATACATTAAAAAATAAAAGTGAGAAAGATTATTTTCAAAATCTTGATAATA
ATATAATGATAATTGCAGATATCAAACTTGAAGAAGCAGAGGAGAGAAGGCATTTTAATGGCTTTGATTATCGTCAGTAT
TTAAAAAGACATGGAATTTATCGTATCGCCAAAGTGACAAAGATAAAACAGATACGCTTATTTCAACATAGGTCTTTCTT
TGATCTTATGTTTAAGTGGCGTAGAAGTGCAATTGTTATTAGTCAAACTTTTCCAAATCCTATGCGTCACTATATGTCAG
GGCTTTTGTTTGGATATCTAGATAAGACCTTTGATGACATGTCCGATTTATATAGTAGTCTAGGTATTATACATTTATTT
GCTTTGTCAGGTATGCAAGTAGGTTTTTTTCTCGGTATTTTTCGTTATATCTGTCTACGTATTGGCTTACGTCTAGACCA
TGTTTGGTTACTTCAAATACCATTCTCGCTAATTTATGCTGGTTTAACAGGCTTTAGTATCTCAGTCGTTAGGGCACTTA
TTCAATCTTTATTATCACATAGCGGTGTCAAGAAAGATGAGAACTTTGCTCTCTGCTTGTTAATTTGTCTTATCTCTCTC
CCCCACTCACTTTTGACTACGGGAGGAGTTCTTAGCTTTGCTTATGCTTTTATACTTACGATGACCTCCTTTGATCATTT
TTCGAGTATAAAAAAAGTAGCTATCGAATCTTTGACAGTCTCTGTAGGAATTCTTCCCATACTAACCTACTATTTTTCGG
GTTTTCAACCAATATCAATTATATTAACAGCACTTTTATCTTTTGCATTTGATATTATATTTTTGCCTTTATTAACTGTT
ATATTTGTCTTATCGCCTATCGTTAAATTAGGTTGTATTAATAGTTTGTTTGAAATCCTAGAAGTGTTATTAAAATGGAC
TGGGCAACTTTTTCCAAGGCCACTTATTTTTGGAAAGCCCAGCCTTTTTCTTTTAATAGTCATGATTATAATTTTGGGAT
TACTTTATGATTATTATCATTCTAAATGTTTTCGTTATTGCTCCCTTCTTATTATCTTTACCTTGTTTTTTATCACTAAG
AATCCAATTACTAACGAGGTTGCGATTTTAGATGTTGGACAGGGAGATAGTATTTTAGTGAGGGATTGGTTAGGAAAAAC
AATTTTAATTGATACTGGGGGAAGGGTGAGATTTGAACAGCCTGAAGAATGGAAACAAAAAGTAAATCAGTCTAATGCTG
AGAGAACGCTCATTCCTTACTTGAAAAGCAGAGGTATTAGCAAGATAGATGATTTAGTGATAACTCATACCGATACAGAT
CATATGGGGGATATGGAAGTTATCTCAAAGCATTTTAAAGTTGCACGTTTGATTACAAGTTCAGGTTCTTTAACGAATTC
GCAGTACGTTAAGCGTTTATCAAAGATAGGTGTAGCGGTAAAATCTATAGAAGCCGGTGATAAACTTGCTGTCATGGGAA
GTTATTTACAAGTACTTTACCCATGGCACAAGGGTGATGGAAAAAATAATGATTCAATTGTTTTATATGGACATTTATTA
GGAAAAGGCTTCTTATTTACCGGTGATTTGGAGGAAGAGGGAGAAAAGCAGTTATTAGAAGCTTATCCTAATTTATCAGT
AGATATCCTTAAAGCAGGACATCATGGTTCTAAGGGCTCATCAAGTCTATCCTTTCTGAAAAAGTTGTCTCCTAGTGTGG
TTCTAGTGTCAGCTGGTAAAAATAATCGTTACCAGCATCCTCATCAAGAGACTTTACAAAGGTTCCAAAAGATTAAAAGC
AAGATTTTCCGAACGGATCAATCAGGTACAATTAGGCTAACAGGATGGTGGAAGTGGCATATTCAGACAGTTCGTTGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (28-177)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-576)

• Competence protein (Competence) (215-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	48.469	100	0.489
comEC/celB	Streptococcus mitis NCTC 12261	48.267	100	0.486
comEC/celB	Streptococcus pneumoniae TIGR4	47.004	100	0.474
comEC/celB	Streptococcus pneumoniae Rx1	46.533	100	0.468
comEC/celB	Streptococcus pneumoniae D39	46.533	100	0.468
comEC/celB	Streptococcus pneumoniae R6	46.533	100	0.468
comEC	Lactococcus lactis subsp. cremoris KW2	44.145	99.732	0.44